Bronchiolar carcinoma is a malignant tumour which apparently arises in a terminal bronchiole from which it spreads either by bronchial embolization or by lymphogenous and/or hematogenous dissemination. It is not a common neoplasm.Histologically, the tumour bears a striking resemblance to the disease of sheep, jagziekte, which is of virus etiology. A very common finding in reported cases is preexisting pulmonary fibrosis. At the Nova Scotia Sanatorium, Kentville, 80 cases of primary lung cancer have been encountered within the past 25 years. Six of these were bronchiolar carcinomas. Five patients had co-existing chronic pulmonary disease, bronchiectasis in one and tuberculosis in four. One patient died of a rapidly progressive bilateral lesion and five were explored. Lobectomy was done in all five, but in one for palliation only. Three patients are alive and well three, six and 14 years, respectively, after their operations.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935181 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Fullerene and fullerene whisker are not carcinogenic to the lungs and pleura in rat long-term study after 2-week intra-tracheal intrapulmonary administration.
Arch Toxicol
December 2024
Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1-Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.
Article Synopsis
- - Fullerene whiskers (FLWs) and fullerenes (FLs) are rod-like structures made of carbon, and their shape raises concerns about potential health risks similar to those posed by asbestos and carbon nanotubes, but no long-term studies on their carcinogenic effects have been conducted.
- - In a study, male rats were given FL, FLW, and different types of multi-walled carbon nanotubes (MWCNT) to assess lung and pleural carcinogenicity, leading to analyses at 1 and 104 weeks post-exposure.
- - Results showed that while MWCNT exposure led to significant increases in lung tumors and oxidative DNA damage, FL and FLW did not induce carcinogenic effects in the
Pulmonary pleomorphic carcinoma arising in mixed squamous and glandular papilloma: A case report.
Thorac Cancer
June 2024
Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Hidaka, Japan.
Solitary pulmonary papillomas (SPPs) are rare lung neoplasms. Histologically, SPP is classified into three subtypes, and mixed squamous and glandular papilloma (MP) is the rarest subtype. Although SPPs are considered benign tumors, there have been several reports on the synchronous malignant transformation in SPPs.
View Article and Find Full Text PDFLongitudinal long term follow up investigation on the carcinogenic impact of polyhexamethylene guanidine phosphate in rat models.
Sci Rep
March 2024
Department of Pathology, Ansan Hospital, Korea University College of Medicine, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi, 15355, South Korea.
Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and lung damage severity with long-term follow-up. Therefore, we evaluated longitudinal dose-dependent changes in lung injuries using repeated chest computed tomography (CT).
View Article and Find Full Text PDFUncommon Tumors of the Lung: Recently Described and Rediscovered Tumors.
Arch Pathol Lab Med
March 2024
From the Department of Pathology, MD Anderson Cancer Center, Houston, TX.
Context.—: The great majority of primary pulmonary neoplasms are represented by non-small cell carcinomas-adenocarcinoma and squamous cell carcinoma. In addition, there is another group of neoplasms such as those of neuroendocrine origin that also represent a meaningful subset of primary lung neoplasms.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!