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Ann Med Interne (Paris)
March 1998
Service de Pharmaco-Toxicovigilance et Centre Anti-Poisons, Hôpital Edouard-Herriot, Pavillon N, 69437 Lyon.
Drug-induced fever is a frequent (3-5% of all adverse effects) but under recognized adverse effect of several drugs. Hydroxyurea, an antimetabolite cytostatic agent, has rarely been involved in the occurrence of fever. We report three additional cases of hydroxyurea-induced fever including one case with pulmonary involvement (acute alveolitis).
View Article and Find Full Text PDFActa Med Port
October 1993
Serviço de Medicina I, Hospital Universitário de Santa Maria, Lisboa.
The authors report the case of a 60-year-old white man with a previous history of pulmonary tuberculosis, smoking habits, hypertension, intermittent claudication and erythromelalgia, admitted to our ward with an ischemic cerebral event. Initial laboratory evaluation documented thrombocytosis (platelet-950000/mm3) and discrete anemia. Additional studies confirmed the diagnosis of essential thrombocythemia, meeting all the criteria proposed by the Polycythemia Vera Study Group in 1986, after exclusion of the possible causes of reactive thrombocytosis.
View Article and Find Full Text PDFRev Rhum Mal Osteoartic
April 1992
Service de Médecine Interne, Diabétologie, Angéiologie, CHU Rouen-Boisguillaume.
The authors report sixteen consecutive cases of erythromelalgia, an infrequent disease in which local heat, redness, and pain develop in the hands and/or feet in recurrent attacks. The disease was essential in nine patients; in the remaining seven, the cause was a myeloproliferative syndrome (polycythemia vera in 3 cases and thrombocythemia in 1 case) or a drug (bromocriptine, nicardipine, and nifedipine, one case each). Acetylsalicylic acid was effective in only six of the nine essential cases.
View Article and Find Full Text PDFRev Esp Enferm Dig
April 1991
Servicio de Cirurgía General y de Urgencia, Hospital General La Paz, Madrid.
A case is presented of mesenteric venous thrombosis which affects about 30 cm of small intestine in a patient operated one month before for portal hypertension and bleeding from esophagogastric varices, in which an interruption of the portal-azygous venous circulation was made with splenectomy, using the Romero-Torres procedure. We consider that postsplenectomy thrombocytosis has been the first pathogenic factor in the mesenteric venous thrombosis.
View Article and Find Full Text PDFMed Clin (Barc)
April 1990
Servicio de Hematología, Hospital Joan XXIII, Tarragona.
We report 3 patients with chronic myeloproliferative syndromes and active tuberculous infection. The first patient had chronic myelocytic leukemia. In this patient, primary tuberculosis was localized in the lung.
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