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Research of novel biocompatible radiopaque microcapsules for arterial embolization.
Int J Pharm
August 2013
Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Embolic agents, such as microparticles, microspheres or beads used in current embolotherapy are mostly radiolucent, which means the agents are invisible under X-ray imaging during and after the process of embolization, and the fate of these particles cannot be precisely assessed. In this research, a radiopaque embolic agent was developed by encapsulating lipiodol in polyvinyl alcohol. The lipiodol-containing polyvinyl alcohol microcapsules (LPMs) were characterized and evaluated for their morphology, size distribution, lipiodol content, lipiodol release, elasticity, and deliverability through catheter.
View Article and Find Full Text PDFEmbolization-driven occlusion of the abdominal aortic aneurysmal sac as the basis of prevention of endoleaks in a new swine model.
Eur J Vasc Endovasc Surg
January 2006
Laboratory of Hemodynamics and Cardiovascular Mechanics, School of Medicine, La Timone Hospital for Adults, Mediterranean See University and Department of Radiology, Marseilles, France.
Objectives: To assess the effect of a new polymer in embolization of endoleaks using an animal model.
Methods: A modified aortic stent-graft was placed in 20 pigs. Embolization was performed at the time of graft insertion with non-cytotoxic n-butyl-2-cyanoacrylate-metacryloxysulpholane and lipiodol (0.
[Experimental concept of periprosthetic membrane neo-flap with axial vascular pedicle].
Ann Chir Plast Esthet
July 1992
Laboratoire de Chirurgie Expérimentale et Microchirurgie, Faculté de Médecine Lariboisière Saint-Louis, Paris.
This study was designed to demonstrate that progressive inflation of an expansion prosthesis placed under the epigastric pedicle of the rat induced the formation of vascular connections between this vessel and the periprosthetic membrane. 17 Wistar rats were operated under general anaesthesia. The 7 cc prosthesis was implanted into the inguinal fold and the valve was placed in a dorsal position via limited incisions.
View Article and Find Full Text PDFLymphograms of 1,000 patients were reviewed with special reference to the occurrence of hepatic oil embolism following the procedure. Oily contrast medium ("Lipiodol" ultra-fluid) was found in the liver in seven cases, five of whom had carcinoma of the cervix uteri. Hepatic oil embolism was not encountered in patients with lymphomas in this series.
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