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The dark side of the association between internet use and older adults' subjective wellbeing: the role of subjective social class.
BMC Geriatr
January 2025
School of Geography & Planning, Sun Yat-sen University, Guangzhou, 510006, China.
Objectives: The majority of studies exploring the relationship between internet use and subjective wellbeing among older adults tend to overlook the mediating mechanisms, particularly psychological ones. Additionally, while research has concluded that internet use is significantly associated with higher levels of subjective wellbeing, it remains unclear whether these associations might become insignificant or negative under certain conditions. To address these gaps, this study investigated the association between internet use and subjective wellbeing in older adults, with a focus on the mediating role of hope and the moderating role of subjective social class.
View Article and Find Full Text PDFThe use of large language models in detecting Chinese ultrasound report errors.
NPJ Digit Med
January 2025
Department of Diagnostic Ultrasound Imaging & Interventional Therapy, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China.
This retrospective study evaluated the efficacy of large language models (LLMs) in improving the accuracy of Chinese ultrasound reports. Data from three hospitals (January-April 2024) including 400 reports with 243 errors across six categories were analyzed. Three GPT versions and Claude 3.
View Article and Find Full Text PDFThe global, regional, and national burden of oral cancer, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
J Cancer Res Clin Oncol
January 2025
Department of General Dentistry II, Peking University School and Hospital of Stomatology, Beijing, People's Republic of China.
Purpose: This epidemiological study leverages data from the Global Burden of Disease (GBD) database spanning from 1990 to 2021 to analyze the global burden of oral cancer. The research aims to provide a comprehensive assessment of the age-standardized incidence rate (ASIR), age-standardized mortality rate (ASDR), and disability-adjusted life years (DALYs) for oral cancer, examining trends over three decades.
Methods: The study used age standardized rate (ASRs) as an indicator of oral cancer epidemiological data.
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer.
Pharmacoecon Open
January 2025
Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Objectives: Immune checkpoint inhibitor (ICI)-containing treatment is currently prescribed as first-line treatment for all patients with advanced non-small cell lung cancer (NSCLC) without targetable driver mutations. However, only 30-45% of patients show no progression within 12 months after treatment start. Various biomarkers are being studied to save costly and potentially harmful treatment in non-responders.
View Article and Find Full Text PDFCoeliac disease: complications and comorbidities.
Nat Rev Gastroenterol Hepatol
January 2025
Takeda Pharmaceuticals, Cambridge, MA, USA.
Coeliac disease is an autoimmune disease characterized by small intestinal villus atrophy and inflammation upon exposure to gluten. It has a global prevalence of approximately 1%. Although the gluten-free diet can be an effective treatment, this diet is burdensome with practical difficulties and frequent inadvertent gluten exposure.
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