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Paraneoplastic pemphigus associated with nonhuman papillomavirus-related tonsillar squamous cell carcinoma: A case report.
Medicine (Baltimore)
September 2024
Department of Otolaryngology, Taipei Medical University Hospital, Taipei, Taiwan.
Article Synopsis
- Paraneoplastic pemphigus (PNP) is a rare autoimmune disease linked to malignancies, with only one known case tied to HPV-positive tonsillar cancer; non-HPV-related cases are extremely rare.
- This study discusses a 58-year-old man with smoking history who developed recurrent oral ulcers and neck swelling, leading to a diagnosis of right tonsillar squamous cell carcinoma that was not associated with HPV, along with indications of PNP.
- The patient successfully underwent surgical treatment and chemotherapy, with follow-up showing no cancer or PNP recurrence, highlighting the importance of diagnosing PNP as a potential indicator of underlying malignancies.
Acute myeloid leukemia with paraneoplastic pemphigus successfully treated with a personalized antileukemic and immunosuppressive strategy.
Ann Hematol
July 2024
Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Roma, 200 - 00128, Italy.
Article Synopsis
- Bullous pemphigoid (BP) is a rare blistering skin disease that may signal underlying cancers, particularly hematological malignancies like acute myeloid leukemia (AML).
- A 28-year-old male patient with both BP and de novo AML was treated using a combination of immunosuppressive therapy and chemotherapy to effectively address both conditions.
- After aggressive treatment, the patient achieved full remission from AML and complete resolution of BP, along with normalized BP180 antibody levels after receiving an autologous stem cell transplant.
Development of Anterior Segment Focused Biologic Therapies to Regenerate Corneal Tissue for the Treatment of Disease: Drug Development Experience.
J Ocul Pharmacol Ther
October 2023
Center for Vision and Eye Banking Research, Eversight, Cleveland, Ohio, USA.
On February 24-27, 2021, the Association for Ocular Pharmacology and Therapeutics (AOPT) held its 15th biennial scientific meeting online. The meeting was organized by Dr. Sanjoy Bhattacharya of the University of Miami in conjunction with the board of trustees of the AOPT.
View Article and Find Full Text PDFUse of Indocyanine Green Fluorescence Imaging in Thoracic and Esophageal Surgery.
Ann Thorac Surg
April 2023
Department of Thoracic and Cardiovascular Surgery, College of Medicine, Korea University Guro Hospital, Seoul, Korea.
Background: Fluorescence imaging using indocyanine green in thoracic and esophageal surgery is gaining popularity because of the potential to facilitate surgical planning, to stage disease, and to reduce postoperative complications. To optimize use of fluorescence imaging in thoracic and esophageal surgery, an expert panel sought to establish a set of recommendations at a consensus meeting.
Methods: The panel included 12 experts in thoracic and upper gastrointestinal surgery from Asia-Pacific countries.
Suprachoroidal Hemorrhage During Descemet Membrane Endothelial Keratoplasty.
Cornea
March 2020
Parker Cornea, Birmingham, AL; and.
Purpose: To describe two cases of suprachoroidal hemorrhage during Descemet membrane endothelial keratoplasty (DMEK).
Methods: Two patients with pseudophakic bullous keratopathy (PBK) underwent DMEK and proceeded to develop intraoperative suprachoroidal hemorrhage. Reports of both cases are documented, including potential risk factors, intraoperative events, and postoperative outcomes and interventions.
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