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Surgical Treatment of Cavernous and Fibrous-Cavernous TB in Children.
Thorac Cardiovasc Surg
January 2023
Department of Phthisiopulmonology and Thoracic Surgery named after M.I. Perelman, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moskva, Russia.
Introduction: Treatment of cavernous and fibrous cavernous tuberculosis in children, especially in the presence of multiple drug resistance-tuberculosis or extremely drug resistance-tuberculosis, presents a major challenge.
Materials And Methods: We analyzed results of treatment of 65 patients (mean age 14.8 + 2.
Impact of pathobiological diversity of Mycobacterium tuberculosis on clinical features and lethal outcome of tuberculosis.
BMC Microbiol
February 2022
St. Petersburg Research Institute of Phthisiopulmonology, St. Petersburg, Russia.
Background: Mycobacterium tuberculosis population in Russia is dominated by the notorious Beijing genotype whose major variants are characterized by contrasting resistance and virulence properties. Here we studied how these strain features could impact the progression of pulmonary tuberculosis (TB) concerning clinical manifestation and lethal outcome.
Results: The study sample included 548 M.
Among 256 patients examined, 145 were diagnosed with multidrug-resistant pulmonary TB: 67 children and 78 teenagers from the focies with the multidrug-resistant TB (the main group), and 111 patients (35 children and 76 teenagers) from the focies with a chemosensitive TB (the control group). Molecular genetic testing of sputum, including the GeneXpert MTB / RIF method and the Hain Lifesciences linear probe analysis, was used to diagnose MRTB. It was found that the pulmonary TB was by 4.
View Article and Find Full Text PDF[Morphological characteristics of pulmonary tuberculosis concurrent with lung cancer].
Arkh Patol
April 2021
Saint Petersburg State Research Institute of Phthisiopulmonology of the Ministry of Health of Russia, St. Petersburg, Russia.
Unlabelled: The pathogenetic relationship between pulmonary tuberculosis and lung cancer in their concurrence is now still the subject of discussion.
Objective: To study the pathogenetic relationship between pulmonary tuberculosis and lung cancer.
Material And Methods: The investigators examined surgical material from 51 patients (41 men) aged 41-73 years (mean age, 63.
Introduction: Epidemics of such dangerous diseases as HIV infection and tuberculosis continue to develop annually. Tuberculosis has become the main cause of mortality in AIDS patients. Both diseases have a negative effect on the state of the immune system, affecting the cells of the lymphatic system.
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