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Diagnostic value of lung function tests in long COVID: analysis of positive bronchial provocation test outcomes.
Front Med (Lausanne)
January 2025
Second Department of Pulmonary and Critical Care Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Background: Long COVID patients are prone to bronchial hyperresponsiveness and respiratory symptoms like coughing and breathing difficulties, often with positive bronchial provocation test (BPT) results.
Objective: This study aims to evaluate the diagnostic value of various lung function tests in patients with long-term COVID-19, explicitly focusing on positive BPT outcomes.
Methods: Our study analyzed the BPT outcomes and various pulmonary function parameters of all 9,406 COVID-19 patients who met the inclusion criteria and visited our hospital between February 24, 2022, and April 28, 2024.
Development and validation of a nomogram for predicting cough variant asthma diagnosis.
BMC Pulm Med
January 2025
Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.
Background: Cough variant asthma (CVA) is a specific type of asthma characterized by chronic cough as the sole or predominant symptom. Accurate diagnosis is crucial for effective treatment, yet bronchial provocation test is not always feasible in clinical settings. To identify independent predictors of CVA diagnosis, we developed a nomogram for predicting CVA.
View Article and Find Full Text PDFGenome-wide association studies (GWAS) have identified genetic variants robustly associated with asthma. A potential near-term clinical application is to calculate polygenic risk score (PRS) to improve disease risk prediction. The value of PRS, as part of numerous multi-source variables used to define asthma, remains unclear.
View Article and Find Full Text PDF[Application value of surface respiratory muscle electromyography and its ratio to tidal volume in the assessment of airway hyperresponsiveness in bronchial asthma patients].
Zhonghua Yi Xue Za Zhi
January 2025
State Key Laboratory of Respiratory Disease/Guangzhou Institute of Respiratory Health/the First Affiliated Hospital of Guangzhou Medical University, Guangzhou510120, China.
To explore the application value of surface respiratory muscle electromyography and its ratio to tidal volume in the assessment of airway hyperresponsiveness in bronchial asthma patients. A case-control study was conducted to retrospectively analyze the data of 29 asthma patients who visited the outpatient department of respiratory medicine of the First Affiliated Hospital of Guangzhou Medical University from October 2015 to May 2017 and 27 non-asthmatic subjects who were recruited as the control group.Changes in surface respiratory muscle electromyography (parasternal, EMG, diaphragmatic, EMG), and its ratio to tidal volume (EMG/VT, EMG/VT) before and after the histamine challenge test were compared between the asthma group and the control group; and their receiver operating characteristic (ROC) curves were plotted.
View Article and Find Full Text PDFBronchial Challenge in the Diagnosis of Cannabis Allergy.
Curr Allergy Asthma Rep
December 2024
Laboratorios INMUNOTEK, Madrid, Spain.
We have read with great interest the recent review published by Dr. Ebo and collaborators on cannabis allergy. It highlights the difficulties in getting a valid diagnosis because some patients do not admit its consumption, which may not be legalized, there are no commercial extracts and there are problems in cutaneous tests interpretation due to cross-reactivity with other related allergens.
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