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Detection and Molecular Diversity of in Pastoral Livestock in North-Eastern Ethiopia.
Pathogens
December 2024
Institute of Biotechnology, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia.
Brucellosis is a neglected zoonotic disease affecting livestock and humans that remains endemic in Ethiopia. Despite its prevalence, only a few studies have identified species circulating in livestock in the country. This study aimed to determine the species responsible for infections in livestock in the Afar region of Ethiopia and characterize the isolates using whole-genome single nucleotide polymorphism (wgSNP) analysis and in silico multi-locus sequence typing (MLST).
View Article and Find Full Text PDFGenetic diversity of Brucella abortus strains from cattle and water buffalo in the Italian province of Caserta.
Vet Microbiol
December 2024
National Reference Centre for Hygiene and Technologies of Water Buffalo Farming and Productions, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Salerno, Italy.
Article Synopsis
- Brucella abortus is a zoonotic pathogen that primarily affects cattle and buffaloes, with ongoing issues of brucellosis in certain areas of Italy, including Caserta.
- Despite eradication programs and vaccination efforts, brucellosis remains endemic in some regions.
- A study sequenced 44 B. abortus strains from 2017-2022 in Caserta and compared them to other Italian strains, revealing low genetic diversity and fewer circulating lineages due to successful eradication efforts.
Seroprevalence and risk factors for brucellosis amongst livestock and humans in a multi-herd ranch system in Kagera, Tanzania.
Front Public Health
November 2024
Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania.
Background: Brucellosis remains a significant health and economic challenge for livestock and humans globally. Despite its public health implications, the factors driving the endemic persistence of at the human-livestock interface in Tanzania remain poorly elucidated. This study aimed to identify the seroprevalence of infection in livestock and humans within a ranching system and determine associated risk factors for disease endemicity.
View Article and Find Full Text PDFRetrospective Analysis of the Epidemiological Evolution of Brucellosis in Animals - China, 1951-1989 and 1996-2021.
China CDC Wkly
November 2024
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Brucellosis poses a significant threat to public health in China. This study utilized a range of epidemiological indices, including seroprevalence and the number of reported cases, to illustrate the epidemic profile of the disease. Although the seroprevalence of brucellosis in animals (including sheep, goats, cattle, and swine) steadily decreased from a severe epidemic level in the 1950s to a low endemic level by 1989, the disease reemerged in 2000.
View Article and Find Full Text PDFMultiple lineages are driving the human brucellosis epidemic in Shaanxi Province, China: evidence from whole genome sequencing-based analysis.
Front Cell Infect Microbiol
November 2024
Department of Plague and Brucellosis, Shaanxi Center for Disease Control and Prevention, Xi'an, China.
Article Synopsis
- Human brucellosis is a significant public health issue in Shaanxi Province, China, and understanding its transmission patterns is essential for creating effective control strategies.
- The study identified 189 strains of the pathogen using bio-typing and whole genome sequencing, revealing genetic diversity with two clades (A and B) and 19 sequence types (STs).
- The findings indicate that the outbreak is fueled by multiple indigenous lineages, highlighting the need for targeted control measures to address this zoonotic disease.
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