One-way mixed lymphocyte reactions in cultures of responding cells from a single subject and a pool of stimulating cells from two or more donors exhibited a synergistic response. Increased activity of the responding cells showed a positive correlation with the pool size. Treatment of the responding cells, stimulating cells or both with neuraminidase significantly increased the response.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422818 | PMC |
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