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Dronedarone a comprehensive drug profile.
Profiles Drug Subst Excip Relat Methodol
January 2025
Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
This comprehensive drug profile provides a detailed exploration of Dronedarone, an antiarrhythmic medication used for regulating irregular heartbeats. This chapter covers various aspects of Dronedarone, including its nomenclature, formulae, physical characteristics, methods of preparation, and analytical methods. The nomenclature section presents the IUPAC and nonproprietary names of Dronedarone, along with its proprietary names.
View Article and Find Full Text PDFNicorandil as a promising therapeutic option for ventricular arrhythmia: A case report and review of literature.
World J Cardiol
December 2024
Department of Cardiovascular Medicine, Affiliated Hospital of Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia Autonomous Region, China.
Background: Ventricular arrhythmia is a common type of arrhythmia observed in clinical practice. It is primarily characterized by premature ventricular contractions, ventricular tachycardia, and ventricular fibrillation. Abnormal formation or transmission of cardiac electrical impulses in patients affects cardiac ejection function.
View Article and Find Full Text PDF[European Society of Cardiology (ESC) guidelines on atrial fibrillation 2024 : What is new and what is important?].
Herz
February 2025
Klinik für Kardiologie, Angiologie, Intensivmedizin, Deutsches Herzzentrum der Charité, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.
Article Synopsis
- * New recommendations include performing transthoracic echocardiography for newly diagnosed AF patients and suggesting SGLT2 inhibitors for heart failure management regardless of left ventricular ejection fraction.
- * The CHA2DS2-VA score now simplifies thromboembolism risk assessment, while pulmonary vein isolation is recommended as a first-line treatment for paroxysmal AF, emphasizing the need for ongoing risk factor evaluation and treatment of related health issues.
A retrospective observational study of certain interactions with simvastatin 40 mg in an acute hospital in England.
Br J Cardiol
May 2024
Head of Prescribing Support Unit Pharmacy Department, Royal Cornwall Hospitals NHS Trust, Truro, Cornwall, TR1 3LJ.
The use of simvastatin 40 mg with various interacting medicines may lead to an increased risk of myopathy. We examined the extent to which hospital inpatients were prescribed simvastatin 40 mg with amiodarone, amlodipine, diltiazem, or verapamil, and assessed if any action was taken by prescribers or the pharmacy team to avoid this interaction. We found 56 patients on a combination of interest during their stay.
View Article and Find Full Text PDFComputer-Aided Identification and Design of Ligands for Multi-Targeting Inhibition of a Molecular Acute Myeloid Leukemia Network.
Cancers (Basel)
October 2024
Izmir Biomedicine and Genome Center, 35340 Balçova, İzmir, Türkiye.
Background/objectives: Acute myeloid leukemia (AML) is characterized by therapeutic failure and long-term risk for disease relapses. As several therapeutic targets participate in networks, they can rewire to eventually evade single-target drugs. Hence, multi-targeting approaches are considered on the expectation that interference with many different components could synergistically hinder activation of alternative pathways and demolish the network one-off, leading to complete disease remission.
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