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Importance: In patients with traumatic brain injury (TBI), baseline pupillary assessment is common. However, the incidence and frequency of pupil abnormalities within the first several days remain poorly characterized.
Objectives: Our aim was to test the association between pupil abnormality frequency over the first 72 hours of admission and clinical outcomes.
Exogenous ketone therapy does not protect brain tissue after moderate-sized intracerebral hemorrhage despite signs of early neurological benefit.
PLoS One
December 2024
Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada.
Ketone bodies, or ketones, are an alternative energy source and have several nonmetabolic signaling actions, such as inhibiting inflammation. Because of this, exogenous ketone supplementation has been used to help treat various diseases. β-hydroxybutyrate (βHB) is the major ketone body that has reduced neurological injury and brain edema in animal models of ischemic stroke and traumatic brain injury.
View Article and Find Full Text PDFMuscle recruitment during gait in individuals with unilateral transfemoral amputation due to trauma compared to able-bodied controls.
Front Bioeng Biotechnol
September 2024
Department of Bioengineering, Imperial College London, London, United Kingdom.
Individuals with transfemoral lower limb amputations walk with adapted gait. These kinetic and kinematic compensatory strategies will manifest as differences in muscle recruitment patterns. It is important to characterize these differences to understand the reduced endurance, reduced functionality, and progression of co-morbidities in this population.
View Article and Find Full Text PDFPrevalence of obstetric violence in high-income countries: A systematic review of mixed studies and meta-analysis of quantitative studies.
Acta Obstet Gynecol Scand
January 2025
Department of Obstetrics and Gynecology, Sygehus Sønderjylland, Aabenraa, Denmark.
Article Synopsis
- Obstetric violence is the mistreatment of women during childbirth and can lead to serious effects like PTSD, fear of childbirth, and depression.
- The study aimed to determine the prevalence of obstetric violence in high-income countries and identify the types of mistreatment women experience, using a comprehensive review of existing research.
- Out of 1821 records, 25 studies were included, revealing a significant obstetric violence prevalence of 45.3%, with specific mistreatment occurrences such as lack of analgesia (17.3%), ignored requests for help (19.2%), and various forms of verbal abuse (19.7%).
Symptom Persistence Relates to Volume and Asymmetry of the Limbic System after Mild Traumatic Brain Injury.
J Clin Med
August 2024
Imgen Research Group, Las Vegas, NV 89118, USA.
: Persistent symptoms have been reported in up to 50% of the 27 million people with mild traumatic brain injuries (mTBI) every year. MRI findings are currently limited by low diagnostic and prognostic sensitivities, constraining the value of imaging in the stratification of patients following mTBI. Limbic system structures are promising brain regions in offering prognostic factors for symptom persistence following mTBI.
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