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The impact of chronic and acute problems on sea turtles: The consequences of the oil spill and ingestion of anthropogenic debris on the tropical semi-arid coast of Ceará, Brazil.
Aquat Toxicol
April 2024
Laboratory of Population Dynamics and Marine Fish Ecology (Dipemar), Institute of Marine Sciences- Federal University of Ceará (LABOMAR-UFC), Av. Abolição, 3207-Meireles, CEP: 60165-081, Fortaleza, CE, Brazil; Tropical Marine Sciences Program/LABOMAR/UFC, Institute of Marine Sciences, Federal University of Ceará (LABOMAR-UFC), Av. Abolição, 3207-Meireles, CEP: 60165-081, Fortaleza, CE, Brazil.
Sea turtle mortality is often related to materials that reach the coast from different anthropic activities worldwide. This study aimed to investigate whether sea turtle mortality was related to older marine problems, such as solid waste, or one of the largest oil spill accidents on the Brazilian coast, that occurred in 2019. We posed three questions: 1) Are there solid residues in the digestive tract samples, and which typology is the most abundant? 2) Can meso‑ and macro-waste marine pollutants cause mortality? 3) Is the dark material found really oil? A total of 25 gastrointestinal content (GC) samples were obtained, of which 22 ingested waste of anthropogenic origin and 18 were necropsied.
View Article and Find Full Text PDFMebendazole targets essential proteins in glucose metabolism leading gastric cancer cells to death.
Toxicol Appl Pharmacol
September 2023
Laboratory of Pharmacogenetics, Drug Research and Development Center (NPDM), Federal University of Ceará, Cel. Nunes de Melo, 1000 - Rodolfo Teófilo, Fortaleza, Brazil. Electronic address:
Gastric cancer (GC) is among the most-diagnosed and deadly malignancies worldwide. Deregulation in cellular bioenergetics is a hallmark of cancer. Based on the importance of metabolic reprogramming for the development and cancer progression, inhibitors of cell metabolism have been studied as potential candidates for chemotherapy in oncology.
View Article and Find Full Text PDFThe Symptom Monitoring with Feedback Trial (SWIFT): protocol for a registry-based cluster randomised controlled trial in haemodialysis.
Trials
May 2022
NHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
Background: Kidney failure prevalence is increasing worldwide. Haemodialysis, peritoneal dialysis or kidney transplantation are undertaken to extend life with kidney failure. People receiving haemodialysis commonly experience fatigue, pain, nausea, cramping, itching, sleeping difficulties, anxiety and depression.
View Article and Find Full Text PDFBiflorin inhibits the proliferation of gastric cancer cells by decreasing MYC expression.
Toxicol In Vitro
March 2020
Faculty of Pharmaceutical Sciences, Federal University of Amazonas, 6200 Rodrigo Octavio Avenue, Manaus, Amazonas, Brazil. Electronic address:
Gastric cancer is the third leading cause of cancer-related death worldwide. To evaluate the anticancer potential and molecular mechanism of biflorin, a prenyl-ortho-naphthoquinone obtained from Capraria biflora L. roots, we used ACP02, a gastric cancer cell line established from a primary diffuse gastric adenocarcinoma.
View Article and Find Full Text PDFVein Suturing Results in Worse Lung Graft Outcomes Compared to the Cuff Method.
Eur Surg Res
March 2020
Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy,
Background: The rat orthotopic lung transplant model is not widely used yet because of the complexity of the procedure, in particular, venous anastomosis. Here, we performed a rat orthotopic lung transplantation using either the suture (ST) or cuff (CT) method for vein anastomosis.
Objectives: To compare the vein ST and CT techniques in terms of operative time, success, recipient survival, and early histological outcomes was the objective of this study.
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