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Comparing approaches for predicting behavioural speech-in-noise performance using cortical responses to unattended stimuli.
Hear Res
January 2025
Institute of Sound and Vibration Research, University of Southampton, Southampton, United Kingdom.
The cortical tracking of the acoustic envelope is a phenomenon where the brain's electrical activity, as recorded by electroencephalography (EEG) signals, fluctuates in accordance with changes in stimulus intensity (the acoustic envelope of the stimulus). Understanding speech in a noisy background is a key challenge for people with hearing impairments. Speech stimuli are therefore more ecologically valid than clicks, tone pips, or speech tokens (e.
View Article and Find Full Text PDFSpreading depolarization triggers pro- and anti-inflammatory signalling: a potential link to headache.
Brain
January 2025
Institute of Neurological Sciences and Psychiatry, Hacettepe University, 06100, Ankara, Turkey.
Cortical spreading depolarization (CSD), the neurophysiological event believed to underlie aura, may trigger migraine headaches through inflammatory signaling that originates in neurons and spreads to the meninges via astrocytes. Increasing evidence from studies on rodents and migraine patients supports this hypothesis. The transition from pro-inflammatory to anti-inflammatory mechanisms is crucial for resolving inflammation.
View Article and Find Full Text PDFEEG-based functional and effective connectivity patterns during emotional episodes using graph theoretical analysis.
Sci Rep
January 2025
Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Understanding the neural mechanisms underlying emotional processing is critical for advancing neuroscience and mental health interventions. This study examined these mechanisms by analyzing EEG connectivity patterns across different brain regions while participants evoked various emotions. After applying independent component analysis (ICA) to eliminate non-cortical activity, we assessed frequency-specific connectivity patterns using coherence, Granger causality, and graph theoretical measures to evaluate both functional and effective connectivity.
View Article and Find Full Text PDFIdentification of a metabolic brain network characterizing essential tremor.
Sci Rep
January 2025
Department of Neurology, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
The neuronal correlate of tremor genesis and cognitive function in essential tremor (ET) and its modulation by deep brain stimulation (DBS) are poorly understood. To explore the underlying metabolic topography of motor and cognitive symptoms, sixteen ET patients (age 63.6 ± 49.
View Article and Find Full Text PDFGranules alleviate brain damage in spontaneously hypertensive rats by modulating the miR-124/STAT3 signaling axis.
Nan Fang Yi Ke Da Xue Xue Bao
January 2025
College of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Objectives: To explore the mechanism of Granules (QDG) for alleviating brain damage in spontaneously hypertensive rats (SHRs).
Methods: Twelve 5-week-old SHRs were randomized into SHR control group and SHR+QDG group treated with QDG by gavage at the daily dose of 0.9 g/kg for 12 weeks.
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