The report contains new data, concerning checking of concepts of interdependence in the reaction development of humoral and cellular immunity from the lateralization of the affected hemisphere (Chuprikov, 1974). A comparative analysis of immunological indices in a local affections of different cortical zones detected that the influence of regulating mechanisms on the cortical level is accompanied by less expressed effects than on the behalf of the hypothalamo-limbic structures. The dominating influence of the left hemisphere was expressed on the development of humoral antibrain reactions while the right hemisphere demonstrated a prevalent influence on the development of reactions of a retarded type to normal and encephalitogenic antigens from the brain.

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