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Biomarker microRNA-371a-3p - expression in malignancies other than germ-cell tumours.
J Cancer Res Clin Oncol
January 2025
Department of Urology, Asklepios Tumorzentrum Hamburg, AK Altona, Hamburg, Germany.
Purpose: microRNA-371a-3p (M371) is considered a highly sensitive and specific serum biomarker of testicular germ cell tumours (GCTs). However, little is known about the expression of M371 in nontesticular malignancies (NTMs), so far. As knowledge about the expression of the marker in other malignancies is a prerequisite for the clinical application of the test we aimed to explore the M371 expression in other cancers.
View Article and Find Full Text PDFThe candidate gene SibHLHA regulates anthocyanin-driven purple pigmentation in Sesamum indicum flowers.
Theor Appl Genet
January 2025
Henan Sesame Research Center, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Anthocyanins not only serve as critical pigments determining floral hues but also play essential roles in attracting insects for pollination, feeding animals and mitigating abiotic stress. However, the molecular mechanisms underlying the regulation of flower color in sesame has not yet been reported. In this study, an F population was constructed by crossing 'Ganzhi 9' (purple-flowered) with 'BS377' (white-flowered).
View Article and Find Full Text PDFIdentification of the CYPome associated with acetamiprid resistance based on the chromosome-level genome of Megalurothrips usitatus (Bagnall) (Thysanoptera: Thripidae).
Pest Manag Sci
January 2025
State Key Laboratory of Green Pesticide, College of Plant Protection, South China Agricultural University, Guangzhou, China.
Background: The bean flower thrips, Megalurothrips usitatus, poses a great threat to cowpea and other legume cultivars. Chemical insecticides have been applied to control M. usitatus, but have resulted in little profit because of the rapid evolution of insecticide resistance.
View Article and Find Full Text PDFCarboxyl Terminal Modulator Protein Induces Cell Senescence and Is Upregulated With Aging by Zic2 in Rats.
J Cell Physiol
January 2025
Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.
Carboxyl terminal modulator protein (CTMP) may be involved in various physiological and pathological processes, such as inflammation, tumor growth, and cardiac hypertrophy. Our recent study has shown that CTMP is increased with aging and plays a role in determining brain ischemic tolerance. However, it is not known how CTMP expression with aging is regulated and whether the changed CTMP expression has an effect on cell senescence.
View Article and Find Full Text PDFAdaptive Laboratory Evolution Uncovers Potential Role of a DNA Helicase Mutation in Torulaspora delbrueckii Increased Sulphite Resistance.
Environ Microbiol
February 2025
Department of Biology, CBMA (Centre of Molecular and Environmental Biology), University of Minho, Braga, Portugal.
Wine industry has faced pressure to innovate its products. Saccharomyces cerevisiae has been the traditional yeast for producing alcoholic beverages, but interest has shifted from the conventional S. cerevisiae to non-Saccharomyces yeasts for their biotechnological potential.
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