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CellStudio: a Modular, Tunable and Accessible Platform for Analysis of Growth Factors Secretions in Cell Cultures.
ACS Appl Mater Interfaces
January 2025
Microfluidics Cluster UPV/EHU, BIOMICs Microfluidics Group, University of the Basque Country UPV/EHU, Vitoria-Gasteiz 01006, Spain.
Traditional cell culture methods face significant limitations in monitoring cell secretions with spatial and temporal precision. Advanced microsystems incorporating biosensors have been developed to address these challenges, but they tend to lack versatility, and their complexity, along with the requirement for specialized equipment, limits their broader adoption. CellStudio offers an innovative, user-friendly solution that exploits Printing and Vacuum Lithography combined with bead-based assays to create modular and tunable cell patterns surrounded by biosensors.
View Article and Find Full Text PDFAssessing plastic ingestion in the White stork (Ciconia ciconia) through regurgitated pellets.
Environ Sci Pollut Res Int
January 2025
Facultad de Ciencias Biológicas, Universidad Complutense de Madrid, Madrid, Spain.
Pollution is one of the main factors that threaten biodiversity nowadays. Plastic waste is a global problem which impacts not only on the marine environment but also on the terrestrial one. Great amounts of this kind of refuse are compiled in landfills, where lots of avian species feed.
View Article and Find Full Text PDFExperiences with HIV stigma, among other barriers, in oral healthcare settings in Türkiye.
AIDS Care
January 2025
Faculty of Medicine, Department of Internal Medicine, Department of Public Health, Hacettepe University, Ankara, Türkiye.
Oral healthcare settings can be a challenging environment for people with HIV. Combined with problematic insurance policies, insufficient health literacy, and higher treatment fees, HIV stigma contributes to barriers when accessing oral healthcare. We conducted a descriptive study via an online survey with open-ended questions to understand the experiences of people with HIV in oral healthcare settings.
View Article and Find Full Text PDFAntiseizure Medications: Advancements, Challenges, and Prospects in Drug Development.
Curr Neuropharmacol
January 2025
Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia.
Epilepsy is a neurological disorder affecting millions of people worldwide. Antiseizure medications (ASM) remain a critical therapeutic intervention for treating epilepsy, notwithstanding the rapid development of other therapies. There have been substantial advances in epilepsy medications over the past three decades, with over 20 ASMs now available commercially.
View Article and Find Full Text PDFDigital Profiling of Immune Biomarkers in Breast Cancer: Relation to Anthracycline Benefit.
Mod Pathol
January 2025
Interdisciplinary Oncology, University of British Columbia, Vancouver, BC, Canada; MAPcore, University of British Columbia, Vancouver, BC, Canada. Electronic address:
Assessment of the tumor immune microenvironment can be used as a prognostic tool for improved survival and as a predictive biomarker for treatment benefit, particularly from immune modulating treatments including cytotoxic chemotherapy. Using Digital Spatial Profiling (DSP), we studied the tumor immune microenvironment of 522 breast cancer cases by quantifying 35 immune biomarkers on tissue microarrays from the MA.5 phase III clinical trial.
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