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Frequency and treatment outcomes of chest wall masses: a 10-year report.
Kardiochir Torakochirurgia Pol
December 2024
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Introduction: Chest wall tumors, though rare, represent a significant subset of thoracic neoplasms, accounting for approximately 5% of thoracic and 2% of overall body neoplasms. Their management has historically posed challenges for surgeons, often leading to misdiagnosis, incomplete resection, and high complication rates. An individualized surgical approach, tailored to the specific characteristics of the disease, is crucial for optimizing outcomes.
View Article and Find Full Text PDFPathologists' integration of prior biopsies of women with germline PTEN mutations may expedite the identification of this rare cancer predisposition syndrome.
Pathology
February 2025
Adult Genetics Unit, Royal Adelaide Hospital, Adelaide, SA, Australia.
Article Synopsis
- PTEN hamartoma tumour syndrome (PHTS) is a rare genetic condition linked to mutations in the PTEN gene, causing increased cancer risks and benign lesions across various organs.
- A study conducted over 28 years examined the biopsy histories of 12 women with PTEN mutations, revealing that most presented with benign mucocutaneous lesions and significant breast cancer development, with only one having a known family history of Cowden syndrome.
- The findings suggest that analyzing past biopsies can help identify underlying cancer susceptibility syndromes like PHTS, leading to better clinical and genetic counseling for affected individuals.
Clinical, radiological, and pathological features of mitotically active cellular fibroma of ovary: A review of cases with literature review.
Taiwan J Obstet Gynecol
September 2024
Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, South Korea; Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea. Electronic address:
Article Synopsis
- The study focuses on mitotically active cellular fibroma (MACF) of the ovary, detailing its clinical, radiological, and pathological characteristics through the analysis of 11 cases between 2015 and 2022.
- The median patient age was 53.7 years, with most presenting symptoms being abdominal pain; tumor sizes varied, and preoperative imaging often misidentified the tumors.
- Results indicate that MACF generally has a benign outcome, and fertility-sparing surgical options are effective, with no disease relapses observed during follow-up, highlighting the importance of intraoperative frozen section for accurate diagnosis.
Intraoperative frozen section evaluation of ovarian sex cord-stromal tumours and their mimics: a study of 121 cases with emphasis on potential diagnostic pitfalls.
Pathology
October 2024
Department of Anatomical Pathology, Division of Pathology, Singapore General Hospital, Singapore. Electronic address:
Article Synopsis
- Ovarian sex cord-stromal tumors (SCSTs) can be hard to identify correctly during quick examinations called frozen sections (FS) because they look different from each other.
- This study looked at 121 cases of SCSTs and found that about 41% of them were accurately diagnosed, while some had wrong diagnoses, mostly with a type called adult granulosa cell tumor (AGCT).
- The researchers discovered that while problems with diagnosing these tumors can happen, no patients were harmed from these errors, and overall, FS accuracy was pretty good at around 78% for different types of tumors.
[Fibromatous Epulis: A Clinical Case Report].
Swiss Dent J
April 2024
Universitäres Zentrum für Zahnmedizin UZB, Klinik für Oralchirurgie.
A 35-year-old patient presented with a painless, broad-based exophytic lesion in the buccal interdental region between teeth 13 and 14. Despite oral hygiene efforts the lesion persisted for around one year. Radiology excluded bone involvement, and histopathology after excision confirmed a fibromatous epulis, which is characterized by collagen-rich connective tissue.
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