The effect of gastric secretion activators with a different mode of action was studied on the qualitative and quantitative composition of sterol in dog gastric juice. Cholesterol was established to be the basic component of the unsaponifiable fraction of both histamine- and insulin-stimulated gastric juice. The presence of unsaponifiable substances and cholesterol was much higher in the histamine-stimulated gastric juice. The data obtained are discussed taking into account the mode of action of the gastric secretion activators.

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