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Adrenaline Dilution in Dental Local Anesthetic Cartridges: A Practical Method Using the Inner Needle of Intravenous Catheter.
Cureus
December 2024
Division of Dental Anesthesiology, Graduate School of Medicine and Dental Sciences, Niigata University, Niigata, JPN.
Local anesthesia is a routine medical procedure for dentists. To achieve the desired anesthetic effect of lidocaine and favorable hemostatic effects by adrenaline, the combination of 2% lidocaine + 1:80,000 adrenaline is commonly used, including in dental patients with underlying diseases for whom adrenaline in local anesthetics is problematic due to its vasoconstrictive effects, as the adrenaline concentration in dental local anesthetic cartridges in Japan is commercially set at 1:80,000. To reduce the effect of adrenaline on the cardiovascular system, adrenaline is sometimes diluted in dental local anesthetic cartridges.
View Article and Find Full Text PDFPostoperative delirium under general anaesthesia by remimazolam versus propofol: A systematic review and meta-analysis of randomised controlled trials.
J Clin Anesth
February 2025
Monash Health School of Clinical Sciences, Monash University, Melbourne, Australia.
Background: Remimazolam, an ultra-short-acting benzodiazepine, has similar clinical effects to propofol for sedation in general anaesthesia. However, it remains uncertain whether remimazolam could increase postoperative delirium (POD) compared with propofol.
Objectives: The purpose of our study was to compare the incidence of POD between remimazolam and propofol as sedative agents in general anaesthesia.
Electroencephalogram-Guided General Anesthesia in a Pediatric Patient With Alexander's Disease: A Case Report.
A A Pract
January 2025
From the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, California.
In this case, the electroencephalogram (EEG) was used to guide anesthesia care for a pediatric patient with Alexander's Disease undergoing serial intrathecal injections. Previous procedures using a standard maintenance propofol dose of up to 225 µg/kg/min led to postanesthetic recovery times of over 6 hours, requiring a neurology consult for noncoherence. The EEG assisted in guiding maintenance propofol dosing to 75 µg/kg/min, decreasing postanesthetic wash-off and postanesthesia care unit (PACU) recovery time by 50%.
View Article and Find Full Text PDFIntravenous Lipid Emulsion for Managing Local Anesthetic Toxicity in a Three-Month-Old Patient.
Cureus
December 2024
Anesthesia Department, King Abdulaziz Medical City, Jeddah, SAU.
Local anesthetic systemic toxicity (LAST) is a well-known life-threatening local anesthetics complication, especially if given in inappropriate doses or routes. Therefore, physicians should be aware of LAST symptoms, such as neurological and cardiac symptoms. In addition, they should always consider it in the differential diagnosis when they encounter similar symptoms.
View Article and Find Full Text PDFEffect of Intravenous Paracetamol on Postoperative Recovery in Children Undergoing Hypospadias Repair under General Anaesthesia with Caudal Block: A Randomised Controlled Trial.
J Coll Physicians Surg Pak
January 2025
Department of Anaesthesiology, The Aga Khan University and Hospital, Karachi, Pakistan.
Objective: To explore the impact of perioperative intravenous (IV) paracetamol, administered with caudal ropivacaine on the quality of postoperative recovery in children undergoing hypospadias repair.
Study Design: Double-blinded randomised controlled trial. Place and Duration of the Study: The operating room, post-anaesthesia care unit (PACU), and paediatric surgical ward at the Aga Khan University Hospital, from 31st January 2019 to 1st May 2022.
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