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Risk and Protective Factors for the Evolution of Subthreshold Depression During Early Adolescence.
J Adolesc Health
January 2025
Laboratory of Cognitive Control and Brain Healthy, Department of Psychology, School of Public Health, Southern Medical University, Guangzhou, China; Department of Psychiatry, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Electronic address:
Purpose: Subthreshold depression refers to a condition involving clinically significant depressive symptoms that fall short of meeting the diagnostic criteria for major depressive disorder (MDD). Identifying risk and protective factors associated with the progression of subthreshold depression in early life is essential for timely prevention. However, there is limited research on this topic among early adolescents.
View Article and Find Full Text PDFThe Clinical Neuroscience of Lucid Dreaming.
Neurosci Biobehav Rev
January 2025
Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.
During most dreams, the dreamer does not realize that they are in a dream. In contrast, lucid dreaming allows to become aware of the current state of mind, often accompanied by considerable control over the ongoing dream episode. Lucid dreams can happen spontaneously or be induced through diverse behavioural, cognitive or technological strategies.
View Article and Find Full Text PDFBaricitinib in early polymyalgia rheumatica (BACHELOR): a randomised, double-blind, placebo-controlled, parallel-group trial.
Lancet Rheumatol
January 2025
Department of Rheumatology, Université de Bretagne Occidentale, CHU Brest, INSERM (U1227), LabEx IGO Brest, France.
Background: Moderate doses of glucocorticoids result in improvements in nearly all patients with polymyalgia rheumatica, but related adverse events are common in older individuals. We aimed to evaluate whether treatment with baricitinib (a Janus kinase 1/2 inhibitor) results in disease control without the use of oral glucocorticoids in people with recent-onset polymyalgia rheumatica.
Methods: We conducted a randomised, double-blind, placebo-controlled, parallel-group trial at six expert centres in France.
Trauma exposure as a risk factor of major depressive disorder: A matched case-control study.
J Psychiatr Res
January 2025
Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen university, 510080, Guangzhou, China; Guangdong Engineering Technology Research Center of Nutrition Translation, 510080, Guangzhou, China. Electronic address:
The association between childhood trauma (CT), stressful life events (SLE) and the onset and severity of major depressive disorder (MDD) has not been extensively studied. This study aimed to investigate the separate and combined association of CT and SLE with the onset and severity of MDD. A total of 503 patients with MDD and 503 controls were included.
View Article and Find Full Text PDFEffects of warm carbon dioxide insufflation vs. local heat on shoulder pain in laparoscopic cholecystectomy: A randomized clinical trial.
J Therm Biol
January 2025
General Surgery, Department of Anesthesiology and Operating Room, School of Allied Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:
Objective: Laparoscopic cholecystectomy is a common procedure for gallbladder diseases, but many patients experience shoulder pain due to pneumoperitoneum. This study investigates the comparative effectiveness of warm carbon dioxide gas insufflation versus local heat application in reducing shoulder pain after laparoscopic cholecystectomy. We also examined changes in body temperature during surgery and postoperative shivering in the intervention and control groups.
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