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Clinical Outcomes after Transcatheter Aortic Valve Implantation in Nonagenarian Patients: a Retrospective Population-Based Cohort Study.
Ann Epidemiol
January 2025
IRCCS Centro Cardiologico Monzino, Department of Cardiovascular Surgery, 20138 Milan, Italy; Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20100 Milan, Italy.
Purpose: To compare the overall survival and the risk of all-cause and heart failure-specific hospitalization in nonagenarian patients hospitalized for symptomatic severe aortic stenosis (AS) who underwent transcatheter aortic valve implantation (TAVI) or conservative treatment.
Methods: Population-based retrospective cohort study based on healthcare utilization databases of the Italian region of Lombardy. The cohort included all nonagenarians hospitalized for AS between 2017 and 2021, who underwent TAVI within 90 days from first diagnosis or conservative treatment.
Social associations across species during nocturnal bird migration.
Curr Biol
January 2025
Cornell Lab of Ornithology, Cornell University, Ithaca, NY 14850, USA; Actions@EBMF, New York, NY 10006, USA.
An emerging frontier in ecology explores how organisms integrate social information into movement behavior and the extent to which information exchange occurs across species boundaries. Most migratory landbirds are thought to undertake nocturnal migratory flights independently, guided by endogenous programs and individual experience. Little research has addressed the potential for social information exchange aloft during nocturnal migration, but social influences that aid navigation, orientation, or survival could be valuable during high-risk migration periods.
View Article and Find Full Text PDFPreclinical evaluation of Ga-labeled folic acid conjugates for visualization of inflammatory foci.
Nucl Med Biol
January 2025
State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 123182 Moscow, Russia. Electronic address:
Introduction: Folate receptors (FR) have been considered a convenient target for different radiopharmaceuticals in recent years. Multifarious Ga-labeled folate conjugates have been proposed as promising agents for the PET imaging of FR-overexpressing malignant neoplasms. In addition, radiolabeled folate-based conjugates can be effective for imaging non-tumor pathological foci characterized by a pronounced cluster of activated macrophages.
View Article and Find Full Text PDFSensitive and specific LAMP and multiplex qRT-PCR assays for detection of hypervirulent Klebsiella pneumoniae.
Diagn Microbiol Infect Dis
January 2025
Department of Clinical Laboratory, DongGuan Song Shan Lake Tungwah Hospital, Dongguan, Guangdong 523820, China. Electronic address:
Hypervirulent Klebsiella pneumoniae (hvKP) pose significant challenges to clinical anti-infective treatment and has emerged as a major threat to global public health. In this study, we employed the loop-mediated isothermal amplification (LAMP) assays with OTG (orange to green) visual dye and multiplex quantitative real-time PCR (qRT-PCR) assay to rapidly detect hvKP. We determined the detection limits of the LAMP methods for K.
View Article and Find Full Text PDFPhotochemical regulation of microcystin synthesis and release in cyanobacteria Microcystis aeruginosa by triplet state dissolved organic matter.
Sci Total Environ
January 2025
College of Environment and Ecology, Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment, Ministry of Education, Chongqing University, Chongqing, 400045, China. Electronic address:
The increasing frequency of cyanobacterial blooms, particularly those induced by Microcystis aeruginosa (M. aeruginosa), poses severe economic, ecological and health challenges due to the production of microcystins (MCs). Environmental parameters such as light and nutrient availability influence MCs production, while the role of dissolved organic matter (DOM) photochemical processes in regulating these remains unclear.
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