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Hand eczema.
Lancet
December 2024
Center for Skin Diseases, Clinic for Dermatology and Allergy, Bonn, Germany. Electronic address:
Hand eczema is a highly prevalent skin disease and one of the most common work-related disorders. In up to two-thirds of individuals affected by hand eczema, the disease becomes chronic and results in substantial personal and occupational disability. Manifestations of chronic hand eczema vary in severity and appearance over time, and people with eczema typically experience itch, pain, and a burning sensation.
View Article and Find Full Text PDFA cross-sectional study of clinical characteristics and risk factors for hand eczema in the general Chinese population.
Sci Rep
November 2024
Department of Dermatology, Wuhan No. 1 Hospital, Wuhan, 430022, China.
In the general population, there is limited evidence for the associations between hand eczema (HE) and lifestyle factors, and between the severity of HE and quality of life. This study aimed to estimate the risk factors for the incidence of HE in the general population and the risk factors for the severity of HE. A cross-sectional questionnaire was administered to 121 HE patients in a hospital from December 2018 to December 2019 in Wuhan.
View Article and Find Full Text PDFDifference between hand and forearm transepidermal water loss and skin pH as an improved method to biomonitor occupational hand eczema: our findings in healthcare workers.
Arh Hig Rada Toksikol
September 2024
Institute for Medical Research and Occupational Health, Division of Occupational and Environmental Health, Zagreb, Croatia.
Article Synopsis
- * It revealed that dental surgeons and dentists had significantly higher transepidermal water loss (TEWL) on their hands compared to their forearms, indicating a concerning level of work-related skin barrier damage.
- * The findings suggested that prolonged use of gloves, along with being male, contributed to worsening skin conditions, emphasizing the importance of monitoring TEWL and pH levels to assess occupational skin health.
Alitretinoin versus phototherapy as the first-line treatment in adults with severe chronic hand eczema: the ALPHA RCT.
Health Technol Assess
October 2024
Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.
Article Synopsis
- Hand eczema is a common skin problem that can be painful and make it hard for people to work, and there isn’t a clear treatment plan agreed on by doctors in the UK.
- This study aimed to compare two treatments, alitretinoin and ultraviolet therapy, to see which works better after 12 weeks for patients with severe hand eczema that didn't improve with regular medicine.
- The results showed that while both treatments helped, alitretinoin was less effective than ultraviolet therapy in reducing the severity of the eczema after 12 weeks.
The association between wet work and hand eczema in the Dutch general population: Application of a job exposure matrix to the lifelines cohort study.
Contact Dermatitis
January 2025
Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Article Synopsis
- This study investigates the link between wet work conditions and moderate-to-very-severe hand eczema (HE) using a job exposure matrix (JEM) in the Dutch general population.
- With data from the Lifelines Cohort Study, researchers found significant connections between various wet work factors and HE, particularly in female participants.
- The findings highlight the need for further observational research to clarify these associations, especially considering the limitations of the JEM approach.
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