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Guinea Worm Disease Presenting as a Subcutaneous Calcification.
Cureus
June 2024
General Surgery, Dr DY Patil Medical College and Hospital, Pune, IND.
A female patient in her early 50s presented with a complaint of multiple right thigh swellings for eight years which on evaluation were found to be guinea worms. The patient had no risk factors as she was living in a rural area of Maharashtra. We performed radiological investigations which only revealed calcifications in subcutaneous planes.
View Article and Find Full Text PDFAdvancing Health Security and Disease Eradication Through Peace and Health: A Mali Case Study.
Health Secur
April 2024
Kashef Ijaz, MD, MPH, is Vice President, Health Programs; at The Carter Center, Atlanta, GA.
Conflict and violence constitute threats to public health. As levels of conflict increase within and between countries, it is important to explore how conflict resolution initiatives can be adapted to meet the health needs of communities, and how addressing the health needs of communities can assist in conflict resolution and contribute to health security. In conflict-affected central Mali, a Peace through Health Initiative, piloted between 2018 and 2022, used conflict resolution trainings, facilitated community meetings, and human and animal health interventions to negotiate "periods of tranquility" to achieve public health goals.
View Article and Find Full Text PDFThe pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use.
Parasit Vectors
October 2023
UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (WHO/TDR), World Health Organization, Geneva, Switzerland.
Article Synopsis
- The World Health Organization (WHO) laid out its objectives for controlling and eliminating neglected tropical diseases (NTDs) in a 2021-2030 roadmap, emphasizing the need for new treatment options and research.
- A review of current anti-infective drug developments reveals that the existing pipeline cannot meet all treatment needs for NTDs, and WHO allows for off-label drug use based on safety and efficacy.
- The article summarizes the lack of clinical research over the past decade on oral small-molecule drugs for numerous NTDs that are neither approved by regulatory authorities nor included in WHO strategies, identifying specific diseases and drugs that have not been thoroughly evaluated.
The article 'Guinea-worm (Dracunculus medinensis) infection presenting as a diabetic foot abscess: A case report from Kerala is being retracted based on a letter received from the Director of the National Centre of Disease Control, New Delhi where the centre has objected to the identification of the guinea-worm by the authors only on the basis of morphological observation, without any microscopic and histopathological examination. The author has agreed to the objection and to the withdrawal of the article. This article is therefore being retracted.
View Article and Find Full Text PDFProgress Toward Global Eradication of Dracunculiasis - Worldwide, January 2021-June 2022.
MMWR Morb Mortal Wkly Rep
November 2022
Dracunculiasis (Guinea worm disease), caused by the parasite Dracunculus medinensis, is acquired by drinking water containing small crustacean copepods (water fleas) infected with D. medinensis larvae. Recent evidence suggests that the parasite also appears to be transmitted by eating fish or other aquatic animals.
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