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Experience-based behavioral and chemosensory changes in the generalist insect herbivore Helicoverpa armigera exposed to two deterrent plant chemicals.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
November 2010
Institute of Zoology, The Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing, 100101, People's Republic of China.
Behavioral and electrophysiological responses of larvae of the polyphagous moth species Helicoverpa armigera to two plant-derived allelochemicals were studied, both in larvae that had been reared on a diet devoid of these compounds and in larvae previously exposed to these compounds. In dual-choice cotton leaf disk and pepper fruit disk arena assays, caterpillars reared on a normal artificial diet were strongly deterred by strychnine and strophanthin-K. However, caterpillars reared on an artificial diet containing strychnine were insensitive to strychnine and strophanthin-K.
View Article and Find Full Text PDFRole of cardiac glycosides in regulation of the growth of retinal tissue explants.
Bull Exp Biol Med
December 2008
Department of Experimental Pharmacology of V. A. Almazov Federal Heart, Blood and Endocrinology Center, Saint-Petersburg, Russia.
We studied the role of cardiac glycosides in the regulation of the growth of retinal tissue explants from 10-12-day-old chicken embryos in organotypic culture. The studied compounds produced a dose-dependent effect on cell proliferation in retinal tissue explants. Ouabain (10(-13)M), strophanthin K (10(-13)M) and digoxin (10(-11)M) significantly stimulated explant growth.
View Article and Find Full Text PDFThe effects of sodium pump inhibitors on sensory ganglion neurite growth.
Neurosci Behav Physiol
March 2009
I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034, St. Petersburg, Russia.
The effects of sodium pump inhibitors of the cardiac glycoside family (strophanthin K and digoxin) on neurite growth in the sensory ganglia of chick embryos (10-12 days) were studied in organotypic tissue cultures. These experiments produced the first evidence that these medicinal agents have marked neurite-suppressing actions. Their effects on sensory ganglion neurite growth were dose-dependent.
View Article and Find Full Text PDF[Effect of Na(+), K(+)-pump inhibitors on the sensory ganglia neurite growth].
Ross Fiziol Zh Im I M Sechenova
March 2008
Inhibitors of Na(+), K(+)-pump belonging to the class of cardiac glycosides were investigated in organotypic tissue culture of dorsal root ganglia cells of 10-12 days old chicken embryos. The data obtained show that the application of cardiac glycosides (strophantin K and digoxin) in a wide range of concentrations controls the neurite growth in sensory neurons in the dose-dependent manner. It was shown, that at the concentrations of cardiac glycoside exceeding 1 x 10(-6) M the growth of neurites was totally inhibited.
View Article and Find Full Text PDF[The effect of hypothermia on kinetic characteristics of the rat brain synaptic membrane Na,K-ATPase].
Ross Fiziol Zh Im I M Sechenova
March 2007
The effect of profound hypothermia (acute or prolonged) on Km for ATP, Vm and strophanthine K affinity to Na,K-ATPase in the rat brain synaptosomal membranes was investigated. The temperature dependence of Na,K-ATPase activity in temperature range 5-40 degrees C was also studied. Hypothermia decreases Km and Vm, and increases affinity of strophanthine K to the enzyme.
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