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Cardioprotective effect of tofisopam against isoprenaline-induced myocardial infarction in rats via modulation of NLRP3\IL-1β\caspase-1 pathway.
Immunopharmacol Immunotoxicol
December 2024
Department of Pharmacology, Faculty of Medicine, Minia University, Minia, Egypt.
Purpose: Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality worldwide. Ischemic heart diseases, particularly acute myocardial infarction (MI), represent the most common cause of death. MI is influenced by multiple factors, including the release of inflammatory mediators.
View Article and Find Full Text PDF[Experience with the therapeutic use of grandaxin in neuroses].
Zh Nevropatol Psikhiatr Im S S Korsakova
August 1982
The use of the drug grandaxin (made in Hungary) has demonstrated its high activity in the treatment of psychopathological disturbances of neurotic origin. Its administration is preferable when vegetative and hyposthenic disturbances are prevalent in the neurosis clinical picture. At the same time it alleviates the intensity of phobic and senestho-hypochondriacal experiences, however, its administration as the sole means for eliminating these disturbances seems undesirable.
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