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Background: During orthotopic liver transplantation, allograft reperfusion is a dynamic point in the operation and often requires vasoactive medications and blood transfusions. Normothermic machine perfusion (NMP) of liver allografts has emerged to increase the number of transplantable organs and may have utility during donation after circulatory death (DCD) liver transplantation in reducing transfusion burden and vasoactive medication requirements.

Methods: This is a single-center retrospective study involving 226 DCD liver transplant recipients who received an allograft transported with NMP (DCD-NMP group) or with static cold storage (DCD-SCS group).

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Trends in blood transfusion and causes of blood wastage: a retrospective analysis in a teaching hospital.

BMC Health Serv Res

January 2025

Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, 666 Buzih Road, Taichung, 40601, Taiwan.

Background: Blood is a vital medical resource that is sourced from primarily nonremunerated donations. As Taiwan faces an aging population, increasing medical demands pose new challenges to blood resource management. Trend analysis can improve blood supply chain management and allocate blood resources more efficiently and cost-effectively.

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Adjunctive Fresh Frozen Plasma Versus Adjunctive Cryoprecipitate in Cardiac Surgery Patients Receiving Platelets for Perioperative Bleeding.

J Cardiothorac Vasc Anesth

December 2024

Department of Critical Care, University of Melbourne, Parkville, Australia; Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, Australia; Data Analytics Research and Evaluation Centre, Austin Hospital, Melbourne, Australia.

Objective(s): This study was designed to assess the relative association between adjunctive fresh frozen plasma (FFP) or adjunctive cryoprecipitate and morbidity and mortality in cardiac surgery patients receiving platelets for perioperative bleeding.

Design: Retrospective cohort study using inverse probability of treatment weighting with entropy balancing.

Setting: Multi-institutional study of 58 centers using the Australian and New Zealand Society of Cardiac and Thoracic Surgeons National Cardiac Surgery Database from January 1, 2005, to December 31, 2021.

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: The coronavirus disease 2019 (COVID-19) pandemic has significantly affected both supply and demand for blood transfusion. This study aimed to investigate the prescription patterns of blood products and identify the risk factors for blood transfusion in patients with severe COVID-19. : This nationwide population-based cohort study was performed in the Republic of Korea between January 2021 and December 2021.

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  • ECMO (extracorporeal membranous oxygenation) is explored as a treatment option for patients with severe ARDS, particularly in burn cases where previous experience is limited.
  • A case study details a 40-year-old woman with significant burns and severe inhalation injury who was placed on veno-venous ECMO for over 21 days while undergoing multiple surgical procedures and receiving extensive blood product transfusions.
  • The report emphasizes the challenges and complexities of managing ECMO support during burn excision surgery, highlighting the need for further research on patient management strategies and the timing of interventions in such cases.
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