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Evaluating the effects of chlorhexidine and vitamin c mouthwash on oral health in non-surgical periodontal therapy: a randomized controlled clinical trial.
Sci Rep
January 2025
Ministry of Health, Ankara Ottoman Oral and Dental Health Center, Ankara, Turkey.
Chlorhexidine (CHX) is the most commonly used mouthwash with proven antiplaque and antibacterial activity. The aim is to evaluate the effect of vitamin C (VitC) in CHX mouthwash on plaque accumulation and gingivitis, and to compare it with CHX alone mouthwash and antiseptic phenol-containing mouthwashes. This study conducted as a multicenter, randomized, controlled, double-blind, parallel design clinical study.
View Article and Find Full Text PDFConservative Approach to Treatment of Cyclosporine-Induced Gingival Hyperplasia With Azithromycin and Chlorhexidine.
Cutis
December 2024
Dr. Krevh is from the College of Medicine, Northeast Ohio Medical University, Rootstown. Dr. Korman is from the Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus.
Treatment of symptomatic cyclosporine-induced gingival hyperplasia can be challenging, especially if continued use of cyclosporine is necessary for adequate control of the underlying disease. We outline a simplified approach for conservatively managing cyclosporine-induced gingival hyperplasia using azithromycin and chlorhexidine.
View Article and Find Full Text PDF[Effects of Chlorhexidine Gluconate Bathing Applied to Cancer Patients on MRSA and VRE Colonization: A Cross-Over Design Study].
Mikrobiyol Bul
January 2025
Hacettepe Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Ankara.
Kanıtlar, klorheksidin glukonat (CHG) solüsyonuyla gerçekleştirilen banyonun, sağlık hizmeti ilişkili enfeksiyonlar (SHİE)'a neden olan mikroorganizmaların kolonizasyonunu azalttığını göstermektedir. Bu çalışmada yoğun bakım ünitesi (YBÜ)'nde yatan kanser hastalarında CHG banyosunun MRSA ve VRE kolonizasyonu üzerindeki etkilerinin değerlendirilmesi amaçlanmıştır. Bu çapraz tasarımlı çalışmada, kanser hastalarında standart su + sabun banyosuyla %2'lik CHG banyosu karşılaştırılmıştır.
View Article and Find Full Text PDFIncidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study.
BMC Pediatr
January 2025
Department of Community and Public Health, Busitema University, Mbale, Uganda.
Background: Omphalitis is a bacterial infection of the umbilicus and/or surrounding tissues, occurring primarily in the neonatal period. Whereas it is known to be a major route of localized and often systemic infection, studies describing incidence and risk factors remain scanty, especially in resource limited settings where the condition is thought to be common. We assessed the incidence and risk factors for omphalitis among neonates born to women who received a birth kit containing chlorhexidine for umbilical cord care after birth in Eastern Uganda.
View Article and Find Full Text PDFIn vitro long-term exposure to chlorhexidine or triclosan induces cross-resistance against azoles in Nakaseomyces glabratus.
Antimicrob Resist Infect Control
January 2025
Division of Clinical Microbiology, Department of Laboratory Medicine, Medical University of Vienna, Vienna, 1090, Austria.
Background: Topical antiseptics are crucial for preventing infections and reducing transmission of pathogens. However, commonly used antiseptic agents have been reported to cause cross-resistance to other antimicrobials in bacteria, which has not yet been described in yeasts. This study aims to assess the in vitro efficacy of antiseptics against clinical and reference isolates of Candida albicans and Nakaseomyces glabratus, and whether prolonged exposure to antiseptics promotes the development of antifungal (cross)resistance.
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