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http://dx.doi.org/10.7326/0003-4819-81-5-584 | DOI Listing |
Microb Biotechnol
November 2018
Department of Civil and Environmental Engineering, National University of Singapore, 1 Engineering Drive 2, Singapore, 117576, Singapore.
Nucleic acid amplification-based methods are limited by their inability to discriminate between viable and dead cells. To overcome this drawback, propidium monoazide (PMA) combined with qPCR has been used to differentiate viable from nonviable cells in environmental samples. However, assessing bacterial physiology using PMA-qPCR remains a challenge due to its incapability of detecting metabolic activities, leading to overestimation of the viable bacteria population under an inactivation condition (e.
View Article and Find Full Text PDFJ Antimicrob Chemother
July 1996
School of Pharmacy, Robert Gordon University, Schoolhill, Aberdeen, UK.
Combinations of either brodimoprim or trimethoprim plus either carbenicillin, gentamicin, ciprofloxacin or rifampicin showed synergy at sub-inhibitory concentrations against both Enterococcus faecalis NCTC 5957 and 775. Brodimoprim alone and in combination showed greater antibacterial activity against both strains of E. faecalis than trimethoprim.
View Article and Find Full Text PDFThe role of lipopolysaccharide (LPS) in determining the permeability of the outer membrane of Pseudomonas aeruginosa to carbenicillin and gentamicin was investigated. The susceptibility of P. aeruginosa isolates to smooth LPS-specific phages and to pyocin R1 gave indirect evidence of an altered LPS structure in strains resistant to carbenicillin, gentamicin, or both.
View Article and Find Full Text PDFBetween October 1980 and October 1981, cefotaxime plus amikacin were used in the treatment of 131 febrile episodes that occurred in 108 neutropenic patients with hematologic malignancies. The overall clinical response was 86.2%.
View Article and Find Full Text PDFCeftazidime was compared with a combination of cephalothin, carbenicillin and gentamicin as empirical therapy for fever in granulocytopenic patients. Forty-eight patients were studied in this randomized trial. In the 44 evaluable cases, favourable clinical responses were seen in 9/21 ceftazidime-treated cases and 13/23 patients treated with the combination.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!