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Background/purpose: Complications, such as postoperative pneumonia, can occur after pediatric cardiac surgery; however, studies on related changes in perioperative oral bacterial counts are scarce. Herein, we investigated the changes in oral bacterial counts before and after surgery in infants who underwent cardiac surgery, as well as after oral care using an antiseptic mouthwash.
Materials And Methods: A total of 102 infants who underwent congenital heart disease surgery were enrolled in this study.
Unlabelled: . resistant to fluoroquinolones and macrolides are serious public health threats. Studies aiming to identify risk factors for drug-resistant have narrowly focused on antimicrobial use at the farm level.
View Article and Find Full Text PDFEffect of Bacterial Nanocellulose with Chemisorbed Antiseptics on Alveolar Bone Repair in Rats Undergoing Bisphosphonate Therapy.
Pharmaceutics
December 2024
Post-Graduate Program in Dentistry, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre 90619-900, RS, Brazil.
: This work investigated the effect of bacterial nanocellulose (BNC) alone or with chemisorbed chlorhexidine or povidone-iodine on post-tooth extraction repair in rats undergoing bisphosphonate therapy. : Forty Wistar rats were treated with zoledronic acid, subjected to tooth extractions and allocated into groups according to the material inserted in the post-extraction socket: (1) BNC ( = 10); (2) BNC/Iodine ( = 10); (3) BNC/Chlorhex ( = 10); (4) Control ( = 10). Maxillae were dissected and macro- and microscopically analyzed.
View Article and Find Full Text PDFL. Herb Extracts: Phytochemical Composition and Pharmacological Activity Screening.
Plants (Basel)
January 2025
Institute of Pharmacy, Faculty of Medicine, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.
The genus (Lamiaceae family) comprises approximately 300 species, which are widely used in traditional medicine for their diaphoretic, antiseptic, hemostatic, and anti-inflammatory properties, but scarcely in official ones. Therefore, the study of holds promise for developing new medicinal products. In aqueous and aqueous-alcoholic soft extracts of the herb, 16 amino acids, 20 phenolics, and 10 volatile substances were identified by HPLC and GC/MS.
View Article and Find Full Text PDFActivity of Antiseptics Against and Its Adaptation Potential.
Antibiotics (Basel)
January 2025
Department of Pharmacognosy and Biomaterials, Poznań University of Medical Sciences, Rokietnicka 3, 60-806 Poznań, Poland.
Background/objectives: rapidly acquires antibiotic resistance and demonstrates increasing tolerance to antiseptics. This study evaluated the activity of eight antiseptics against , assessed its ability to develop adaptation to these antiseptics, and, for the first time, determined the Karpinski Adaptation Index (KAI) for this bacterium.
Methods: The minimal inhibitory concentration (MIC), susceptibility to antibiotics, bactericidal time according to EN 1040:2005, adaptation potential, and KAI of strains were evaluated.
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