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Microbial and chemically induced reductive dechlorination of polychlorinated biphenyls in the environment.
Environ Sci Pollut Res Int
January 2025
The State University of New York College of Environmental Science and Forestry, Syracuse, USA.
Polychlorinated biphenyls (PCBs) are persistent organic pollutants and are emitted during e-waste activities. Once they enter into the environment, PCBs could pose toxic effects to environmental compartments and public health. Reductive dechlorination offers a sustainable solution to manage the PCBs-contaminated environment.
View Article and Find Full Text PDFGene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus).
Biol Open
January 2025
Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543,USA.
Coastal fish populations are threatened by multiple anthropogenic impacts, including the accumulation of industrial contaminants and the increasing frequency of hypoxia. Some populations of the Atlantic killifish (Fundulus heteroclitus), like those in New Bedford Harbor (NBH), Massachusetts, USA, have evolved a resistance to dioxin-like polychlorinated biphenyls (PCBs) that may influence their ability to cope with secondary stressors. To address this question, we compared hepatic gene expression and DNA methylation patterns in response to mild or severe hypoxia in killifish from NBH and Scorton Creek (SC), a reference population from a relatively pristine environment.
View Article and Find Full Text PDFStochastic marine ecosystem modeling for statistical interpretation of the uncertainty factors used for the determination of tolerable daily intake of polychlorinated biphenyls.
Environ Pollut
December 2024
Department of Systems Design for Ocean-Space, Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya, Yokohama, Kanagawa, 2408501, Japan. Electronic address:
This study developed a numerical simulation model for a marine ecosystem to determine accumulation levels of polychlorinated biphenyls (PCBs) in top predators (seabasses). The simulated results were used for calculating probabilities of exceeding tolerable daily intake (TDI) of seafoods enforced by the US and Japanese governments. The model was applied to Tokyo Bay, Japan.
View Article and Find Full Text PDFPersistent organic pollutants and endogenous sex-related hormones in Hispanic/Latino adults: The Hispanic Community health study/study of Latinos (HCHS/SOL).
Environ Res
December 2024
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, USA.
Background: Previous studies have demonstrated associations of persistent organic pollutants (POPs) with sex-related hormones; however, findings were inconsistent. Sex-specific impacts and pathways through which adiposity influences associations are not completely understood. We sought to evaluate sex-specific associations of POPs serum concentration with sex-related hormones and to explore pathways through which adiposity may modify associations.
View Article and Find Full Text PDFTwo Hits of EDCs Three Generations Apart: Evaluating Multigenerational Anxiety-Like Behavioral Phenotypes in Male Rats Exposed to Aroclor 1221 and Vinclozolin.
Environ Health Perspect
December 2024
Division of Pharmacology & Toxicology, The University of Texas at Austin, Austin, Texas, USA.
Background: Increasing evidence supports an association of endocrine-disrupting chemical (EDC) exposures with adverse biological effects in humans and wildlife. Recent studies reveal that health consequences of environmental exposures may persist or emerge across generations. This creates a dual conundrum: that we are exposed to contemporary environmental chemicals overlaid upon the inheritance of our ancestors' exposure profiles.
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