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Rationale and Ethical Assessment of an Oropharyngeal Gonorrhoea Controlled Human Infection Model.
J Infect Dis
January 2025
Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Infection with Neisseria gonorrhoeae, the causative agent of gonorrhoea, causes significant morbidity worldwide and can have long-term impacts on reproductive health. The greatest global burden of gonorrhoea occurs in low- and middle-income settings. Global public health significance is increasing due to rising antimicrobial resistance (AMR), which threatens future gonorrhoea management.
View Article and Find Full Text PDFCommunity pharmacies: Key players in point-of-care diagnostics for STI screening in Africa.
PLoS One
January 2025
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Background: Sexually Transmitted Infections (STIs) rank in the top 5 disease categories for which adults in developing countries seek healthcare services. Community pharmacies offer clients convenience, proximity, extended opening hours, privacy, and efficiency, which could make them desirable locations for HIV and STI screening and treatment. We examined the feasibility of using point-of-care (POC) STI tests for screening HIV and other STIs at community pharmacies.
View Article and Find Full Text PDFHigh Prevalence of Sexually Transmitted Infections and Poor Sensitivity and Specificity of Screening Algorithms for Chlamydia and Gonorrhea Among Female Sex Workers in Zimbabwe: Analysis of Respondent-Driven Sampling Surveys in 3 Communities.
Sex Transm Dis
February 2025
Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Background: Effective strategies to reduce sexually transmitted infection burden and transmission among female sex workers (FSWs) and their networks are needed. We report sexually transmitted infection prevalence among FSWs in Zimbabwe and investigate the performance of screening algorithms.
Methods: Respondent-driven sampling (RDS) surveys, including blood sampling for syphilis serology, were conducted among FSWs in 3 communities in Zimbabwe in 2017.
Could have carcinogenic potential? A critical review of current evidence.
Crit Rev Microbiol
January 2025
School of Biomedical Sciences at Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, QLD, Australia.
There is growing evidence that microbial dysbiosis is intimately related to carcinogenesis across several types of human cancer. is best known for causing acute exudative genitourinary infection in males. can also cause chronic, asymptomatic infection of the female genitourinary tract along with the oropharynx and rectum of both sexes.
View Article and Find Full Text PDFScreening for STIs: Results of a Health-Promotion Programme in a Portuguese University.
Microorganisms
December 2024
CERES, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.
Sexually Transmitted Infections (STIs) are an important and growing public health concern. Implementation of screening programmes and awareness campaigns are crucial to mitigate this problem. A university in the central region of Portugal has devised a health-promotion programme, named , specifically directed towards the sexual health of the university community.
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