AI Article Synopsis
- The study examined the fine structure of neurofibrillary tangles in various brain regions of 5 autopsy cases of Progressive Supranuclear Palsy.
- Only straight filaments, measuring 150 A wide, were found in the tangles analyzed.
- These results support previous research on neurofibrillary tangles in this condition and indicate that the previously noted link between straight and twisted filament tangles may be rare.
Article Abstract
The fine structure of subcortical neurofibrillary tangles was investigated in pallidum, substantia nigra, periaqueductal gray, pontine reticular gray, and dentate nucleus of 5 autopsy cases of Progressive Supranuclear Palsy. Only tangles due to straight 150 A wide filaments have been detected. These findings, obtained from a large series of cases and areas examined, confirm previous observations on the fine structure of neurofibrillary tangles in Progressive Supranuclear Palsy and suggest that the association between tangles due to straight filaments and tangles due to twisted tubules, so far described in one case, is probably exceptional.
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| http://dx.doi.org/10.1007/BF00691893 | DOI Listing |
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