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Intraspecific genetic diversity with unrestricted gene flow in the domoic acid-producing diatom Nitzschia navis-varingica (Bacillariophyceae) from the Western Pacific.
Harmful Algae
January 2025
Bachok Marine Research Station, Institute of Ocean and Earth Sciences, University of Malaya 16310 Bachok, Kelantan, Malaysia. Electronic address:
The benthic pennate diatom Nitzschia navis-varingica, known for producing domoic acid (DA) and its isomers, is widely distributed in the Western Pacific (WP) region. To investigate the genetic differentiation and gene flow patterns among the populations in the WP, the genetic diversity of 354 strains of N. navis-varingica was analysed using two nuclear-encoded rDNA loci: the large subunit rDNA (LSU rDNA) and the internal transcribed spacer 2 (ITS2).
View Article and Find Full Text PDFFabrication of curcumin-loaded nano-micelles based on quercetin-quarternary ammonium-chitosan (Qu-QCS) conjugate and evaluation of synergistic effect with doxorubicin against breast cancer.
Int J Biol Macromol
November 2024
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand; Drug Delivery System Excellent Center, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand. Electronic address:
The applications of quarternized chitosans have achieved notable success in the development of drug-delivery systems. This study reported the preparation of quercetin-quarternized chitosan (Qu-QCS) conjugate and its application for the fabrication of stable and safe curcumin (cur) loaded nano-micelles with high targeting ability and selectivity towards the breast cancer cell lines. Moreover, doxorubicin (dox) was co-treated with the nanomicelles to enhance the efficacy and reduce the cardiotoxic effects of dox.
View Article and Find Full Text PDFFrom Double-Stranded Helicates to Abiotic Double Helical Supramolecular Assemblies.
Chemistry
January 2025
Adionics, The Advanced Ionic Solution, 17 bis avenue des Andes, 91940, Les Ulis, France.
The folding of oligomeric strands is the method that nature has selected to generate ordered assemblies presenting spectacular functions. In the purpose to mimic these biomacromolecules and extend their properties and functions, chemists make important efforts to prepare artificial secondary, tertiary, and even quarternary structures based on folded abiotic backbones. A large variety of oligomers and polymers, encoded with chemical informations, were designed, synthesized and characterized, and the establishment of non-covalent interactions lead to complex and functional supramolecular architectures resulting from a spontaneous self-assembly process.
View Article and Find Full Text PDFNa[GeF]·2HF: the first quarternary phase in the H-Na-Ge-F system.
Acta Crystallogr C Struct Chem
August 2024
Department Chemie, Ludwig-Maximilians Universität München, Butenandtstrasse 5-13 (Haus D), D-81377 München, Germany.
The structure of cis- or trans-bridged [GeF] anionic chains have been investigated [Mallouk et al. (1984). Inorg.
View Article and Find Full Text PDFDemographic patterns of two related desert shrubs with overlapping distributions in response to past climate changes.
Front Plant Sci
February 2024
State Key Laboratory Breeding Base of Desertification and Aeolian Sand Disaster Combating, Gansu Desert Control Research Institute, Lanzhou, China.
Article Synopsis
- Studies show that geological events and climate changes significantly impact species' genetics and populations, but related species can respond differently to these changes.
- This research focused on two desert shrubs in northern China, analyzing their genetic structure using chloroplast DNA from 633 individuals across 52 populations, identifying 24 chlorotypes, including a widely dominant one.
- The results indicated varying genetic diversity and population structures related to habitat preferences, with one species showing demographic expansion in the past, while the other did not, and both species' distributions fluctuated over time due to climatic changes.
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