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[Extra-membranous glomerulonephritis: from the experimental model to the human pathology of new-born and adult].
Bull Mem Acad R Med Belg
December 2008
Unité Inserm UMR S702 et Département de Néphrologie, Hôpital Tenon, Paris, France.
Membranous nephropathy (MN) is one of the most common glomerulopathies. Current treatments are entirely empirical, and concept-driven therapies are dramatically lacking. In the rat experimental model established by Heymann in 1959, the target antigen is expressed at the surface of podocytes where immune complexes are formed, inducing complement activation results in heavy proteinuria.
View Article and Find Full Text PDF[Glomerulopathy during Behçet's syndrome. Immunofluorescent and electron microscopy studies (author's transl)].
Ann Med Interne (Paris)
December 1979
Full renal investigation were conducted in 11 patients with Behçet's syndrome. Biological tests revealed the presence of mild proteinuria in 5 of them. Needle biopsy showed extra-membranous or mesangial fibrinoid deposits in 6 cases, associated in 1 case with segmental and focal glomerulitis lesions.
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