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Risk of authoritarianism: fibrinogen-transmitted hepatitis C in Japan.

Lancet

December 2007

Department of Planning, Information and Management, University of Tokyo Hospital, Tokyo, Japan.

In 1977, the US Food and Drug Administration revoked all licences for fibrinogen concentrate because of the risk for hepatitis infection and suspected lack of effectiveness. However, in Japan, fibrinogen concentrate was used routinely for treatment of obstetric bleeding until 1988. Even in 1997, academic texts by Japanese authorities in obstetrics still recommended that obstetricians use the product.

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