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Metastatic papillary thyroid carcinoma in the soft tissue of the breast in a male patient: A case report.
Oncol Lett
February 2025
Department of Radiology, University Hospital Olomouc, Olomouc 77900, Czech Republic.
Papillary thyroid carcinoma (PTC) represents ~80% of all thyroid cancers, most frequently presenting in women in the third and fourth decade of life. The first clinical manifestation of PTC commonly includes a palpable mass in the thyroid area or cervical lymphadenopathy in cases of metastatic disease. Hematogenous distant metastases are a sign of an advanced stage of the tumour.
View Article and Find Full Text PDFBackground: Mesothelioma is an aggressive malignancy of the serosal surfaces with very poor prognosis. It traditionally manifests in older patients and at an advanced stage which results in minimal improvement in prognosis despite the recent advances in management. Early detection would therefore significantly impact management and potentially improve survival.
View Article and Find Full Text PDFPostautologous Hematopoietic Stem Cell Transplantation Disseminated Hypopigmented Keratosis.
Am J Dermatopathol
December 2024
Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; and.
Disseminated hypopigmented keratosis is a rare distinct clinical entity. This report describes the case of a 19-year-old male patient who developed disseminated hypopigmented keratosis 2 months after autologous hematopoietic stem cell transplantation for pineal choriocarcinoma. The patient displayed numerous tiny whitish or depigmented macules and papules on the chest, back, posterior neck, shoulders, arms, and thighs, closely resembling lichen nitidus.
View Article and Find Full Text PDFSpatial transcriptomics identifies RBM39 as a gene a Gleason score progression in prostate cancer.
iScience
December 2024
Department of Urology, Beijing Tongren Hospital, Capital Medical University, Beijing 100176, P.R. China.
Article Synopsis
- Prostate cancer (PCa) is complex and often shows multiple tumor regions with different levels of severity, which this study investigated using advanced techniques like spatial transcriptomics to look at gene expression patterns in areas with different Gleason scores (GSs).
- The analysis revealed clear relationships between gene expression and the histological characteristics of varying GSs, showcasing how tumor malignancy increases as the Gleason score rises.
- A specific gene, RBM39, was notably linked to GS progression through gene comparison techniques, and this finding was validated with additional data from the Cancer Genome Atlas, as well as through laboratory experiments.
Tuberculous parotitis: A case series diagnosed on fine needle aspiration.
IDCases
November 2024
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Introduction: Tuberculosis (TB) remains a global health concern with diverse clinical manifestations. Parotid tuberculosis, although rare, presents diagnostic challenges due to its atypical presentation. Cytological examination is pivotal in diagnosing parotid lesions.
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