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Atrial Septal Defect vs Ventricular Septal Defect: Getting the Right Mix in Transposition of the Great Arteries.
Cureus
April 2024
Pediatric Cardiology, Great Ormond Street Hospital, London, GBR.
Article Synopsis
- Transposition of the great arteries (TGA) is a serious heart defect affecting about 4.7 in 10,000 newborns, leading to low oxygen levels right after birth.
- Initial treatment includes medications like prostaglandins and possibly a procedure called balloon atrial septostomy, depending on the patient's condition.
- A specific case study highlighted complications in a patient with TGA alongside other heart issues, and following a surgical procedure, the child required further intervention, ultimately leading to improved health and discharge.
Palliative interatrial septum stenting with a vascular stent in a chronic thromboembolic pulmonary hypertension patient: Is it beneficial?
Egypt Heart J
August 2023
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, 11420, Indonesia.
Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious disease that can progress and lead to a deadly outcome. Despite optimal drug therapy, pulmonary hypertension (PH) remains fatal. Untreatable right heart failure (RHF) from CTEPH is eventually a significant cause of death.
View Article and Find Full Text PDFIs low-risk status a surrogate outcome in pulmonary arterial hypertension? An analysis of three randomised trials.
Lancet Respir Med
October 2023
Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Clinical Trials Methods and Outcomes Lab, Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:
Article Synopsis
- The study investigates whether short-term risk scores for pulmonary arterial hypertension (PAH) can predict long-term outcomes like clinical worsening and mortality in patients.
- It uses data from three randomized clinical trials, analyzing risk assessments from various PAH risk score tools and their correlation with adverse clinical events.
- Results indicated significant insights into the potential of these risk scores as surrogates for predicting long-term survival and health deterioration in PAH patients.
Impact of Bedside Balloon Atrial Septostomy in Neonates with Transposition of the Great Arteries in a Neonatal Intensive Care Unit in Romania.
Life (Basel)
April 2023
Department of Pediatric Cardiology, M.S. Curie Children's Clinical Hospital, 041451 Bucharest, Romania.
(1) Background: Transposition of the great arteries (TGA) is the most common congenital heart disease, accounting for 5-7% of all cardiac anomalies, with a prevalence of 0.2-0.3 per 1000 live births.
View Article and Find Full Text PDFPalliative Procedures for Congenital Heart Disease: Imaging Findings and Complications.
Radiographics
April 2023
From the Department of Radiology, Mayo Clinic, 200 1st St SW, Rochester, MN 55905-0002 (P.S.R.); Speciality Hospital, IMMS Western National Medical Center, Guadalajara, Mexico, and UdG, Health Science University Center, Guadalajara, Mexico (M.J.S.); Department of Cardiology, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa (R.A.); and Pediatric Hospital, Western National Medical Center, IMSS, Guadalajara, Mexico, and Imaging and Diagnostic Center CID, Guadalajara, Mexico (H.G.).
Palliative procedures are performed for congenital heart diseases that are not amenable for definitive surgical procedures or as a component of hybrid procedures along with transcatheter interventions. Multimodality imaging plays an important role in the follow-up of these palliative procedures, mainly for the timely detection of complications and for planning any subsequent palliative or definitive procedure. Echocardiography is the first-line imaging modality, with CT and MRI used as complementary techniques in indeterminate cases.
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