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A systematic literature review of the effectiveness of tick-borne encephalitis vaccines in Europe.
Vaccine
November 2023
Vaccines, Antivirals, and Evidence Generation, Pfizer Biopharma, Collegeville, PA, United States. Electronic address:
Article Synopsis
- Tick-borne encephalitis (TBE) is an infectious disease caused by the tick-borne encephalitis virus, prevalent in over 25 European nations, where two vaccines (FSME-IMMUN® and Encepur®) are commonly administered but lack robust real-world effectiveness reviews.
- A systematic search of studies in PubMed identified 13 studies from various European countries (2003-2023) which showed that TBE vaccines were highly effective (over 92% effectiveness) against TBEV infection and severe outcomes, across all age groups.
- The findings suggest that TBE vaccines significantly prevent thousands of TBE cases annually, avoiding hospitalizations and fatalities, although detailed effectiveness data is still limited to a few countries
Tick-borne encephalitis (TBE) is a central nervous system zoonotic disease transmitted by ticks. Tick-borne encephalitis virus (TBEV) is one of the main causes of lymphocytic meningitis in the areas of its endemic occurrence. A mode of transmission of TBEV which is rarely observed in clinical practice is an alimentary transmission through consumption of unpasteurised dairy products from infected animals.
View Article and Find Full Text PDFMilk-borne diseases through the lens of one health.
Front Microbiol
April 2023
Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, India.
Reviewing "zoonotic diseases" classically brings to mind human infections contracted in close association with animals, where outdoor occupations and afforested lands usually play a key role in the epidemiological triad. However, there is a very common, yet overlooked route of infection where humans may not come in direct contact with animals or implicated environments. Milk-borne diseases are a unique set of infections affecting all age groups and occupational categories of humans, causing 4% of all the foodborne diseases in the world.
View Article and Find Full Text PDFDetection of hepatitis E virus in milk: Current evidence for viral excretion in a wide range of mammalian hosts.
Transbound Emerg Dis
November 2022
ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.
Infection with hepatitis E virus (HEV) is common in both developing and industrialized nations. Genotypes 3 and 4 are increasingly being reported, particularly in high-income countries where the precise extent of HEV transmission via food is currently unclear. Recently, HEV has been found to be excreted in milk; however, data on the potential milk-borne transmission is still lacking or conflicting and warrants further research on the topic.
View Article and Find Full Text PDFInvestigation of Brucellosis Caused by Raw Goat Milk - Fujian Province, China, April-June, 2019.
China CDC Wkly
May 2021
Chinese Center for Disease Control and Prevention, Infectious Diseases Management Office, Beijing, China.
Brucellosis is one of the most important zoonotic diseases in China. Goat milk and dairy products are essential pathways for foodborne transmission of brucellosis. Pasteurization can completely kill spp in milk, and milk-borne transmission is mainly related to unhealthy dietary hygiene habits and insufficient epidemic control among animals.
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