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[Next generation sequencing in pediatric bone marrow failure: a valuable tool for accurate diagnosis].
Andes Pediatr
October 2024
Facultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia.
Unlabelled: Inherited Bone Marrow Failure syndromes account for approximately 25% of cases of aplastic anemia in pediatric patients. Next-generation sequencing (NGS) technologies have allowed the diagnosis of an increasing number of hereditary causes of bone marrow failure.
Objective: To determine the diagnostic yield and clinical concordance of NGS in the diagnosis of a cohort of pediatric patients with bone marrow failure.
Visual and fluorescence dual mode platform for sensitive and accurate screening of breast carcinoma.
Biosens Bioelectron
March 2025
TCM and Ethnomedicine Innovation & Development International Laboratory, School of Pharmacy, Hunan·University of Chinese Medicine, Changsha, China. Electronic address:
Compared to single-mode detection, dual-mode sensing strategies have garnered increasing attention from researchers due to their superior detection accuracy and reliability. Exosomes, as non-invasive biomarkers, hold significant potential for disease diagnosis. However, sensitive and precise detection of exosomes still presents considerable technical challenges.
View Article and Find Full Text PDFField integration of shoot gas-exchange and leaf chlorophyll fluorescence measurements to study the long-term regulation of photosynthesis in situ.
Tree Physiol
January 2025
Optics of Photosynthesis Laboratory, Institute for Atmospheric and Earth System Research (INAR)/Forest Sciences, Viikki Plant Science Center, Latokartanonkaari 7-9, 00014 University of Helsinki, Helsinki, Finland.
Understanding the diurnal and seasonal regulation of photosynthesis is an essential step to quantify and model the impact of the environment on plant function. Although the dynamics of photosynthesis have been widely investigated in terms of CO2 exchange measurements, a more comprehensive view can be obtained when combining gas-exchange and chlorophyll fluorescence (ChlF). Until now, integrated measurements of gas-exchange and ChlF have been restricted to short-term analysis using portable infrared gas analyzer systems that include a fluorometer module.
View Article and Find Full Text PDFPeptide-Based Rapid and Selective Detection of Mercury in Aqueous Samples with Micro-Volume Glass Capillary Fluorometer.
Biosensors (Basel)
November 2024
Department of In Vitro Studies, Institute of Biotechnology and Molecular Medicine, 80-180 Gdansk, Poland.
Mercury, a toxic heavy metal produced through both natural and anthropogenic processes, is found in all of Earth's major systems. Mercury's bioaccumulation characteristics in the human body have a significant impact on the liver, kidneys, brain, and muscles. In order to detect Hg ions, a highly sensitive and specific fluorescent biosensor has been developed using a novel, modified seven amino acid peptide, FY7.
View Article and Find Full Text PDFPlasma cell-free DNA as predictor of disease status in patients with differentiated thyroid cancer - a prospective study from a tertiary care institution.
Front Oncol
October 2024
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Introduction: Plasma cell-free DNA (cfDNA) estimation offers a non-invasive method to potentially diagnose, monitor, and prognosticate patients with malignancy. This prospective study aimed to assess plasma cfDNA levels in patients with differentiated thyroid cancer (DTC) to determine its role in predicting disease status in the post-operative setting.
Materials And Methods: This was a single-center prospective observational study conducted at a public medical research university and hospital in New Delhi, India.
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