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A Case of Malignant Pleural Effusion Complicated by Klebsiella rhinoscleromatis.
Cureus
October 2024
Internal Medicine, Unidade Local de Saúde de Castelo Branco, Castelo Branco, PRT.
This case report describes an elderly man with a history of alcohol use disorder and primary malignant liver neoplasm who presented to the emergency department with dyspnea, asthenia, fever, and signs of respiratory distress. Diagnostic tests, including a chest radiograph and computed tomography, revealed a large left-sided exudative pleural effusion with regular and diffuse pleural enhancement, a large tumor lesion in the left lobe with diaphragmatic and pleural invasion, and a liver with features suggestive of cirrhosis. Laboratory data showed increased inflammatory markers and hyperlactacidemia.
View Article and Find Full Text PDFClassic ketogenic diet-induced ketoacidosis in the treatment of pyruvate dehydrogenase deficiency: a case report and literature review.
BMC Pediatr
September 2024
Department of Pediatrics, Peking Union Medical College Hospital (PUMCH), Beijing, 100730, China.
Article Synopsis
- PDC deficiency is a rare mitochondrial disorder that disrupts glucose metabolism, resulting in neurological issues and high lactic acid levels, leading to metabolic acidosis.
- A 6-year-old patient diagnosed with PDC deficiency experienced severe ketoacidosis when starting the ketogenic diet (KD), but this was managed by adjustments in diet and dextrose supplementation.
- This case emphasizes the need for careful management of KD, particularly by starting with a lower ketogenic ratio to mitigate the risk of metabolic disturbances in patients with PDC deficiency.
From Bronchodilation to Lactic Acidosis: A Case Report on Salbutamol's Adverse Effect.
Cureus
June 2024
Intensive Care Department, Centro Hospitalar Lisboa Ocidental, Lisbon, PRT.
Article Synopsis
- - Asthma is a common chronic respiratory condition marked by hyper-responsiveness of the airways and occasional obstruction, with short-acting β agonists (SABA) being the main treatment for acute episodes.
- - A case is reported where a young female patient experienced lactic acidosis after being treated with SABA, specifically salbutamol, for severe acute asthma; this was linked to her treatment despite showing significant improvement in breathing.
- - After stopping the SABA treatment, the patient's symptoms, including respiratory distress and elevated lactate levels, improved quickly, and she was discharged after five days; this incident highlights the rare but important side effect of lactic acidosis associated with SABA use.
CARDIOGENIC SHOCK AND GLOBUS PALLIDUS INJURY AS A PRESENTATION OF CARBON MONOXIDE POISONING.
Ann Burns Fire Disasters
June 2024
Intensive Care Unit, Professor Doutor Fernando Fonseca Hospital, Amadora, Portugal.
Carbon monoxide poisoning is one of the leading causes of mortality and morbidity by poisoning in the world. Signs and symptoms are nonspecific and related to impaired oxygen delivery to tissues, with the brain being the most affected organ due to its high oxygen demand. CO-Hb is a poor indicator of severity and long-term outcome, with clinicians relying more on clinical features such as level of consciousness and need for intubation, organ dysfunction and shock and also pH level.
View Article and Find Full Text PDF[Analysis of a child with developmental disorder and epilepsy due to a homozygous variant of SLC25A12 gene].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
July 2024
Department of Pediatric Neurology, Guangzhou Women and Children's Medical Center Liuzhou Hospital, Liuzhou, Guangxi 545616, China.
Objective: To explore the genetic basis for a child featuring global developmental delay and epilepsy.
Methods: A child who had presented at Guangzhou Women and Children's Medical Center Liuzhou Hospital on February 19, 2023 was selected as the study subject. Clinical data of the child was collected.
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