According to our material the exfoliation glaucoma can be regarded as the result of an interplay of at least two different pathologic conditions: a primary genetic goniodysgenesis creating a relative block to the outflow, and a probable vasculopathy in the iris. Subsequent degeneration of the iris will lead to a liberation of pigment and debris, i.e., the exfoliation syndrome, eventually causing obliteration of the outflow pathways.
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