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Current management of neonatal abstinence syndrome: a survey of practice in the UK and Ireland.
Arch Dis Child Fetal Neonatal Ed
April 2024
Department of Paediatrics, Regional Hospital Mullingar, Mullingar, Westmeath, Ireland
Objective: To study the current management practices of neonatal abstinence syndrome (NAS) throughout the UK and Ireland and identify changes in practice from the most recent survey in 2008.
Design: Postal questionnaire to a consultant paediatrician or neonatologist in all 215 neonatal units in the UK and Ireland in January 2020.
Results: Response rate was 62%.
Factors associated with euphoria in a large subset of cases using propofol sedation during gastrointestinal endoscopy.
Front Psychiatry
April 2023
Department of Anesthesiology, Peking University Third Hospital, Beijing, China.
Background: The utilization of Propofol, a widely used intravenous sedative or anesthetic, is characterized by its quick onset, predictable control, and fleeting half-life during both general anesthesia and intensive care unit sedation. Recent evidence, however, has highlighted propofol's propensity to induce euphoria, particularly in patients undergoing painless procedures such as gastrointestinal or gastric endoscopy. Given its widespread use in patients undergoing such procedures, this study aims to investigate the clinical evidence and factors that may influence propofol-induced euphoria in these settings.
View Article and Find Full Text PDFAnaesthesia of decapod crustaceans.
Vet Anim Sci
June 2022
Bio-Resources Unit, National University of Ireland Galway, University Road, Galway H91TK33, Ireland.
Decapod crustaceans (crabs, hermit crabs, lobsters, crayfish, shrimps, prawns) are sentient beings, not only responding to noxious stimuli but also being capable of feeling pain, discomfort, and distress. General anaesthesia aims at producing analgesia, immobilization, and unconsciousness, while sedation reduces consciousness, stress, and anxiety, though without analgesia. Anaesthesia is recommended to ensure animal welfare and suppress nociception, pain, and suffering in painful and distressing practice that impairs decapods' welfare.
View Article and Find Full Text PDFA chemiluminescence sensor array for discrimination of seven toxicants.
Luminescence
December 2021
School of Forensic Medicine, Shanxi Medical University, Jinzhong, China.
A chemiluminescence (CL) sensor array was developed based on 11 CL systems cross-combined by three luminescence reagents and four oxidants. Using the CL sensor array, we measured seven toxicants, including morphine, ketamine, diazepam, chlorpromazine, strychnine, paraquat, and fenpropathrin, which represent psychotropic drugs, sedatives and hypnotics, rodenticides, herbicides, and insecticides, respectively. The CL response pattern or 'fingerprints' were obtained for a given compound on the sensor array and then discriminated through principal component analysis.
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