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Rapid acclimatization to baseline stimulation with a multi-canal vestibulocochlear implant.
Eur Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, School for Mental Health and Neuroscience (MHENS), Maastricht University Medical Centre, Maastricht, The Netherlands.
Purpose: It is hypothesized that a vestibular implant should re-establish baseline activity of the ampullary nerves. Use of a constant baseline stimulation potentially allows encoding of bi-directional head movements, through the addition of signal modulations. Effective stimulation of the vestibular nerves depends on the ability to acclimate to this baseline signal.
View Article and Find Full Text PDFThe effect of dietary supplements on core temperature and sweating responses in hot environmental conditions: a meta-analysis and meta-regression.
Am J Physiol Regul Integr Comp Physiol
January 2025
A-STEM Centre, Faculty of Science and Engineering, Swansea University, Swansea, UK.
Dietary supplements are widely used among individuals exposed to hot environments, but whether their consumption confers any thermoregulatory effect is unclear. Therefore, we systematically evaluated the effect of dietary supplementation on key aspects of thermoregulation (core temperature [T] and sweating responses) in the heat. Three databases were searched in April 2024.
View Article and Find Full Text PDFRole of autophagy in plant growth and adaptation to salt stress.
Planta
January 2025
Biological and Geological Sciences Department, Faculty of Education, Ain Shams University, Cairo, 11341, Egypt.
Under salt stress, autophagy regulates ionic balance, scavenges ROS, and supports nutrient remobilization, thereby alleviating osmotic and oxidative damage. Salt stress is a major environmental challenge that significantly impacts plant growth and agricultural productivity by disrupting nutrient balance, inducing osmotic stress, and causing the accumulation of toxic ions like Na. Autophagy, a key cellular degradation and recycling pathway, plays a critical role in enhancing plant salt tolerance by maintaining cellular homeostasis and mitigating stress-induced damage.
View Article and Find Full Text PDFMortality and diurnal temperature range in Virginia.
Int J Biometeorol
January 2025
Southeast Regional Climate Center, Department of Geography and Environment, University of North Carolina, Chapel Hill, NC, 27514, USA.
The relationship between diurnal temperature range (DTR) and daily mortality from 2005 to 2020 is examined for seven large metropolitan areas in Virginia using distributed lag non-linear models that control for temperature and humidity. The relative risk of mortality increases for very high DTR, and there is a short lag effect of several days. High risk DTR days are rare, typically occurring less than 1% of the time at most locations.
View Article and Find Full Text PDFCold induces brain region-selective cell activity-dependent lipid metabolism.
Elife
January 2025
Department of Medicine, Division of Endocrinology, Albert Einstein College of Medicine, Bronx, United States.
It has been well documented that cold is an enhancer of lipid metabolism in peripheral tissues, yet its effect on central nervous system lipid dynamics is underexplored. It is well recognized that cold acclimations enhance adipocyte functions, including white adipose tissue lipid lipolysis and beiging, and brown adipose tissue thermogenesis in mammals. However, it remains unclear whether and how lipid metabolism in the brain is also under the control of ambient temperature.
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