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Molecular Characterization, Oxidative Stress-Mediated Genotoxicity, and Hemato-Biochemical Changes in Domestic Water Buffaloes Naturally Infected with Under Field Conditions.
Pathogens
January 2025
Department of Pharmacology and Toxicology, Faculty of Biosciences, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
(1) Background: Surra is a debilitating disease of wild and domestic animals caused by (), resulting in significant mortality and production losses in the affected animals. This study is the first to assess the genetic relationships of in naturally affected buffaloes from Multan district, Pakistan, using ITS-1 primers and evaluating the effects of parasitemia and oxidative stress on DNA damage and hematobiochemical changes in infected buffaloes. (2) Methods: Blood samples were collected from 167 buffaloes using a multi-stage cluster sampling strategy, and trypomastigote identification was performed through microscopy and PCR targeting RoTat 1.
View Article and Find Full Text PDFRisk Factors Associated with Hemoparasites in Dual-Purpose Cattle of Colombia.
Pathogens
January 2025
Centro de Investigación Turipaná, Corporación Colombiana de Investigación Agropecuaria AGROSAVIA, km 13 vía Montería, Cereté 230550, Colombia.
Hemoparasitic diseases represent a significant problem with a considerable impact on tropical and subtropical areas of the world. These conditions cause economic losses associated with multi-organic failure and even the death of animals. In these areas, the hemoparasites are transmitted in an enzootic cycle when infectious cattle, such as persistently infected animals, including cows, contribute to the success of transmission.
View Article and Find Full Text PDFEpidemiology of Chagas Disease in the United States of America: A Short Review and Some Comments.
Pathogens
January 2025
Division of Infectious Diseases, University of Arizona, 5701 North Campbell Ave., Tucson, AZ 85719,USA.
The epidemiology of Chagas disease in humans has markedly changed within the past several decades in the United States of America. This report discusses autochthonous cases of Chagas disease as well as disease in immigrants from Latin American countries. Suggestions for epidemiology research and medical care are discussed given the evolving epidemiology of the disease in the United States of America.
View Article and Find Full Text PDFFirst report of Trypanosoma microti in Cricetid rodents from Querétaro, Mexico: Expanding the known distribution of Herpetosoma in the Mexican transition zone.
Vet Parasitol Reg Stud Reports
January 2025
C.A. Ecología y Diversidad Faunística, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Santiago de Querétaro, Mexico; Licenciatura en Medicina Veterinaria y Zootecnia, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Santiago de Querétaro, Mexico. Electronic address:
Members of the subgenus Herpetosoma are specialized parasites of mammals of the order Lagomorpha and Rodentia. It is estimated that around 50 species within this subgenus are transmitted by several flea species. These parasites have recently gained attention from a public health perspective because several species have been reported to infect humans.
View Article and Find Full Text PDFIsolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine sp. Cyanobacterium.
Org Lett
January 2025
Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Human African trypanosomiasis (HAT) is one of the most lethal of the neglected tropical diseases. While the discovery of a novel antitrypanosomal drug is highly desired, the creation of a superior lead compound is challenging. Herein we report ukabamide (), which was isolated from a marine sp.
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