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Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a rare, symmetrical skin eruption triggered by various medications, predominantly beta-lactam antibiotics. We report the case of a 69-year-old male with moderate-to-severe ulcerative colitis who developed SDRIFE following the seventh intravenous administration of infliximab. The patient presented with symmetrical, pruritic erythema in the cubital and popliteal fossae, groins, gluteal and retroauricular regions without systemic involvement.

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Now-a-days, all over the world, skin disease are the fourth most common cause of disability. A significant amount of patient attending the dermatology outdoor of any major hospital in a daily basis. Irrational drug prescribing is a common contemplation in clinical practice.

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Surgical Site Allergic Contact Dermatitis to 2-Octyl-Cyanoacrylate: A Systematic Review and FDA MAUDE Review.

Aesthet Surg J

December 2024

Division of Plastic and Reconstructive Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Background: Skin adhesives containing 2-ocyl cyanoacrylate are a common source of allergic contact dermatitis (ACD) that complicate postoperative wound healing. There are limited studies that describe postoperative cutaneous reactions to skin adhesives and clinical management.

Objectives: To review the incidence, description, and clinical management of surgical site ACD to 2-ocyl cyanoacrylate.

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Article Synopsis
  • A systematic review aimed to analyze global AD management guidelines for children, particularly focusing on those with skin of colour, assessing the quality of these guidelines from 1990 to 2023.
  • The review identified 28 guidelines, revealing inconsistencies in management recommendations, insufficient updates on newer therapies, and a significant lack of guidance regarding AD in people with skin of colour, with only 12 out of 28 guidelines meeting quality standards.
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Topical nasal therapy represents a widespread opportunity to treat upper airway diseases. As a result, specialists in different areas (mainly ENT, pediatrics, and allergology) and general practitioners prescribe intranasal compounds. However, a myriad of products and devices are available, as well as respiratory disorders.

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