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The weepy cry - short neural signal bursts in intraoperative neuromonitoring.
Langenbecks Arch Surg
March 2024
Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.
Purpose: This study aimed to establish an in-vitro alternative to existing in-vivo systems to analyze nerve dysfunction using continuous neuromonitoring (C-IONM).
Methods: Three hundred sixty-three recurrent laryngeal nerves (RLN) (N = 304, N = 59) from food industry cadavers were exposed by microsurgical dissection following euthanasia. After rinsing with Ringer's lactate, they were tempered at 22 °C.
Medical Honey in Head and Neck Cancer.
Cureus
January 2024
Otolaryngology, University of Texas Medical Branch, Galveston, USA.
Medical honey has been recognized for its medicinal properties for thousands of years, and several medical honey products have entered the market over the last two decades. In vitro studies have shown that honey has antimicrobial properties, protects against bacterial growth, and improves wound healing. However, these products are not widely used for wound treatment in head and neck surgery.
View Article and Find Full Text PDFResearch progress of plant-derived natural products in thyroid carcinoma.
Front Chem
January 2024
The Affiliated Jiangyin People's Hospital of Nantong University, Jiangyin, China.
Thyroid carcinoma (TC) is a prevalent malignancy of the endocrine system, with a notable rise in its detection rate in recent decades. The primary therapeutic approaches for TC now encompass thyroidectomy and radioactive iodine therapy, yielding favorable prognoses for the majority of patients. TC survivors may necessitate ongoing surveillance, remedial treatment, and thyroid hormone supplementation, while also enduring the adverse consequences of thyroid hormone fluctuations, surgical complications, or side effects linked to radioactive iodine administration, and encountering enduring physical, psychosocial, and economic hardships.
View Article and Find Full Text PDFEffects of maternal hypothyroidism on postnatal cardiomyocyte proliferation and cardiac disease responses of the progeny.
Am J Physiol Heart Circ Physiol
October 2023
Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States.
Maternal hypothyroidism (MH) could adversely affect the cardiac disease responses of the progeny. This study tested the hypothesis that MH reduces early postnatal cardiomyocyte (CM) proliferation so that the adult heart of MH progeny has a smaller number of larger cardiac myocytes, which imparts adverse cardiac disease responses following injury. Thyroidectomy (TX) was used to establish MH.
View Article and Find Full Text PDFCasein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling.
Int J Mol Sci
April 2023
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Casein kinase 1α (CK1α) is present in multiple cellular organelles and plays various roles in regulating neuroendocrine metabolism. Herein, we investigated the underlying function and mechanisms of CK1α-regulated thyrotropin (thyroid-stimulating hormone (TSH)) synthesis in a murine model. Immunohistochemistry and immunofluorescence staining were performed to detect CK1α expression in murine pituitary tissue and its localization to specific cell types.
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