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Introduction: Arterial vascular occlusion is a rare complication of dermal filler injection. This case report describes the successful use of hyperbaric oxygen therapy in a patient with vascular occlusion after a permanent dermal filler was injected.

Case Report: A 51-year-old woman underwent an injection of non-resorbable polymethylmethacrylate microspheres into her nasolabial folds.

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Objectives: The main objective was to evaluate the cost-effectiveness of various medical therapy combinations in managing chronic coronary syndrome (CCS) in Iran, based on real-world and patient-level data.

Design: A cost-utility analysis employing a Markov model was conducted using data from a retrospective cohort study.

Setting: The study was conducted in the healthcare setting of Iran, focusing on primary and secondary care.

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Introduction: Patients with heart failure exacerbation can present in a variety of ways, including sympathetic crashing acute pulmonary edema (SCAPE). Emergency physicians play a key role in the diagnosis and management of this condition.

Objective: This narrative review evaluates key evidence-based updates concerning the diagnosis and management of SCAPE for the emergency clinician.

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Drugs associated with tachyphylaxis: results from a retrospective pharmacovigilance study using disproportionality analysis.

Eur J Hosp Pharm

January 2025

Pharmacology & Therapeutics, College of Medicine and Health Sciences, Arabian Gulf University, Manama, Bahrain

Background: Tachyphylaxis is the rapid development of drug tolerance following repeated administration.

Objectives: To evaluate the United States Food and Drug Administration Adverse Event Reporting System (USFDA AERS) data for drugs significantly associated with tachyphylaxis using disproportionality analysis.

Methods: Disproportionality analysis was used for detecting safety signals for identifying drugs associated with tachyphylaxis.

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The Efficacy of Heparin and Nitroglycerin in Managing Vascular Embolism Complications from Polycaprolactone (PCL) Fillers: A Clinical Study.

Aesthetic Plast Surg

January 2025

Department of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, No.389 Xincun Road, Shanghai, 200092, China.

Background: The use of PCL fillers has increased due to their long-lasting effects and collagen stimulation properties. However, managing vascular embolisms caused by PCL fillers is challenging due to the inability to dissolve them quickly. This study builds upon our previous findings from animal studies, which provided valuable insights into the management of PCL-related vascular complications.

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