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Iron pigment deposits, small vessel vasculitis, and erythrophagocytosis in the muscle of human immunodeficiency virus-infected patients.
Hum Pathol
December 1991
Département de Pathologie (Neuropathologie), Hôpital Henri Mondor, Créteil, France.
Hemosiderin deposition and vascular inflammation were evaluated in muscle specimens from 50 human immunodeficiency virus (HIV)-infected individuals with neuromuscular symptoms. Iron deposits were detected in 25 of 50 cases, and were found more frequently in the distal muscles of lower limbs than in proximal muscles (22 of 30 cases v three of 20 cases; P less than .001).
View Article and Find Full Text PDFHuman recombinant leukocyte interferon-alpha induces intracytoplasmic tubuloreticular structures and crystalline bodies in Kaposi's sarcoma cells in vivo.
Arch Dermatol Res
January 1991
Department of Molecular Cell Pathology, Gesellschaft für Strahlen- und Umweltforschung mbH München, Federal Republic of Germany.
Membranous changes in primary malignant CNS lymphomas.
Acta Neuropathol
January 1990
Department of Neuropathology, National Institute of Neurosurgery, Budapest, Hungary.
Ultrastructural studies of 17 primary malignant CNS lymphomas revealed 6 tumors with abnormal intracytoplasmic and/or intranuclear membranous structures, most frequently associated with the endoplasmic reticulum or perinuclear envelope. In most cases, tubuloreticular inclusions and paired cisternae were present. Less frequent were accumulation of microtubules, concentric lamellar bodies, and rod-like or paracrystalline intranuclear inclusions.
View Article and Find Full Text PDFRenal tissues from two groups of patients with acquired immune deficiency syndrome (AIDS) were examined: Group A had severe proteinuria and varying degrees of renal insufficiency, designated AIDS-associated nephropathy (AAN), and Group B had no renal involvement. Control Group C consisted of patients with heroin-associated nephropathy (HAN) with proteinuria comparable to patients in Group A but without AIDS or its related complex (ARC). The most frequent finding, common to both AAN and HAN, was focal glomerular sclerosis.
View Article and Find Full Text PDFUltrastructural pathology of dendritic spines in epitumorous human cerebral cortex.
Acta Neuropathol
July 1987
Ultrastructural changes in the human epitumorous cerebral cortex were examined. A swelling of nerve cell perikarya, dendrites and axon terminals, and an occasional hyperplasia and disarray of microtubules and neurofilaments were observed. Accumulations of lysosomes, tubuloreticular structures and intracytoplasmic or intramitochondrial crystalloid inclusions were also found.
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