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Indian J Pharmacol
May 2017
Department of Community Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
Objective: Treatment of chronic urticaria (CU) can be difficult in many patients. Achieving long-term remission and reducing the requirement of antihistamines are vital in CU. The objective of this study was to assess the effectiveness of injection histaglobulin, a complex of histamine and human immunoglobulin, in producing relief in patients with CU.
View Article and Find Full Text PDFInt Immunopharmacol
April 2003
Institut für Molekulare Medizin und Zellforschung, AG Tumorimmunologie/Vakzine, Universitätsklinikum Freiburg, Stefan-Meier-Str 8, D-79104 Freiburg, Germany.
Vaccination with the antiallergic drug Histaglobin is used to treat a broad range of human allergic diseases including bronchial asthma, allergic rhinitis, and atopic dermatitis. In order to further elucidate its functional activity, Histaglobin was investigated in an in vivo mouse allergy model. Mice were sensitized with ovalbumin either prior to or after Histaglobin treatment, and its antiallergic potential was evaluated.
View Article and Find Full Text PDFAim: To evaluate therapeutic effects of histaglobin drugs (histaglobin and histaglobin-triplex) in patients with continuous allergic rhinitis (CAR) and chronic recurrent (idiopathic) urticaria (CRU).
Materials And Methods: The drugs were given to 45 patients with CAR and high sensitivity to household allergens confirmed by cutaneous diagnostic tests or high IgE level, and 40 patients with CRU with typical cutaneous lesions. The drugs were injected subcutaneously (a total of 6 injections, 2 ml of solution each) with the interval 2-3 or 3-4 days.
J Allergy Clin Immunol
December 1997
Department of Allergology, Institute of Bio-Active Science, Nippon Zoki Pharmaceutical Company, Hyogo, Japan.
A complex of histamine/human gamma-globulin (HhG) has been widely used in Japan for more than 25 years as a nonspecific hyposensitization drug in the treatment of allergic diseases. It has been reported that HhG decreases the number of eosinophils in the nasal secretions and peripheral blood of patients with allergy. In this study we used a mouse system to explore the possibility that HhG may actively inhibit the accumulation of eosinophils at inflammation sites.
View Article and Find Full Text PDFPneumonol Alergol Pol
June 1993
Kliniki Chorób Wewnetrznychi i Alergologii AM, Wroclawiu.
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