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Cancer incidence and competing mortality risk following 15 presenting symptoms in primary care: a population-based cohort study using electronic healthcare records.
BMJ Oncol
November 2024
Department of Behavioural Science and Health, Institute of Epidemiology and Healthcare, University College London, London, UK.
Objectives: Assessment of age, sex and smoking-specific risk of cancer diagnosis and non-cancer mortality following primary care consultation for 15 new-onset symptoms.
Methods And Analysis: Data on patients aged 30-99 in 2007-2017 were extracted from a UK primary care database (CPRD Gold), comprising a randomly selected reference group and a symptomatic cohort of patients presenting with one of 15 new onset symptoms (abdominal pain, abdominal bloating, rectal bleed, change in bowel habit, dyspepsia, dysphagia, dyspnoea, haemoptysis, haematuria, fatigue, night sweats, weight loss, jaundice, breast lump and post-menopausal bleed).Time-to-event models were used to estimate outcome-specific hazards for site-specific cancer diagnosis and non-cancer mortality and to estimate cumulative incidence up to 12 months following index consultation.
The effect of dietary supplements on core temperature and sweating responses in hot environmental conditions: a meta-analysis and meta-regression.
Am J Physiol Regul Integr Comp Physiol
January 2025
A-STEM Centre, Faculty of Science and Engineering, Swansea University, Swansea, UK.
Dietary supplements are widely used among individuals exposed to hot environments, but whether their consumption confers any thermoregulatory effect is unclear. Therefore, we systematically evaluated the effect of dietary supplementation on key aspects of thermoregulation (core temperature [T] and sweating responses) in the heat. Three databases were searched in April 2024.
View Article and Find Full Text PDFCorrelation between night sweats and season fluctuation in China.
Front Public Health
January 2025
Shandong Academy of Chinese Medicine, Jinan, China.
Background: Night sweats are a condition in which an individual sweats excessively during sleep without awareness, and stops when they wake up. Prolonged episodes of night sweats might result in the depletion of trace elements and nutrients, affecting the growth and development of children.
Purpose: To investigate the relationship between sweat nights and season.
Sweating the small stuff: microclimatic exposure and species habitat associations inform climate vulnerability in a grassland songbird community.
Biol Lett
January 2025
Department of Forest and Wildlife Ecology, University of Wisconsin-Madison,1630 Linden Drive, Madison, WI 53706, USA.
Assessment of species' vulnerability to climate change has been limited by mismatch between coarse macroclimate data and the fine scales at which species select habitat. Habitat mediates climate conditions, and fine-scale habitat features may permit species to exploit favourable microclimates, but habitat preferences can also constrain their ability to do so. We leveraged fine-resolution models of near-surface temperature and humidity in grasslands to understand how microclimates affect climatic exposure and demographics in a grassland bird community.
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